ZHC-116 Impurity 3 CAS 1256782-94-1
| CAS No. | 1256782-94-1 |
| Molecular Formula | C21H27F3N4O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of ZHC-116 Impurity 3 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
ZHC-116 Impurity 3 (CAS 1256782-94-1) is a certified pharmaceutical impurity reference standard with the molecular formula C21H27F3N4OHCl and a molecular weight of 444.93 g/mol.
ZHC-116 Impurity 3 (C21H27F3N4OHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures ZHC-116 Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H27F3N4O 2*HCl |
| Molecular Weight | 444.93 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- Terbutaline Impurity 14 (CAS 30923-82-1)
- Acetylcysteine Impurity 19 (CAS 2885-79-2)
- Dabrafenib Impurity 2 (CAS CATO-C4X-30332)
- (2R,3R,4S)-2,3,4,5-Tetrahydroxy-3-(hydroxymethyl)pentanal (CAS 99247-35-5)
- (3-Chloro-2-methoxypyridin-4-yl)methanol (CAS 1227586-24-4)
- Ethyl 2-(2-(1-bromoethyl)-4-oxoquinazolin-3(4H)-yl)acetate (CAS 216596-60-0)
- 2-Chloro-N-phenylquinolin-4-amine (CAS 824935-59-3)
- 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (CAS 121577-32-0)
- Tert-butyl (((2R,4R)-4-(trifluoromethyl)pyrrolidin-2-yl)methyl)carbamate (CAS 2306246-16-0)
- FMRF-Like Peptide from snail Helix aspersa (CAS 98495-35-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com