Dabrafenib Impurity 2 CAS CATO-C4X-30332
| CAS No. | CATO-C4X-30332 |
| Molecular Formula | C24H24FN5O3S2 |
| Molecular Weight | 513.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dabrafenib Impurity 2 is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Dabrafenib Impurity 2 (CAS CATO-C4X-30332, C24H24FN5O3S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Dabrafenib Impurity 2 (C24H24FN5O3S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H24FN5O3S2 |
| Molecular Weight | 513.61 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Dabrafenib Standards
- Dabrafenib Impurity 1 (CAS 2017554-98-0)
- Dabrafenib Impurity 13 (CAS CATO-C4X-303313)
- Dabrafenib Impurity 40 (CAS CATO-C4X-303340)
- Dabrafenib (CAS 1195765-45-7)
- Dabrafenib Impurity 30 (CAS CATO-C4X-303330)
- Dabrafenib Impurity 18 (CAS 1622082-84-1)
- Dabrafenib Impurity 26 (CAS CATO-C4X-303326)
- Dabrafenib Impurity N1 (CAS 1195765-47-9)
Recommended Standards
- Gliquidone Impurity 6 (CAS 57081-83-1)
- Cesium triiodide (CAS 12297-72-2)
- Edoxaban Impurity 83 (CAS CATO-C4X-106383)
- N-(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl Omeprazole-d3 Sulfone (CAS 1346603-82-4)
- Gadodiamide Impurity 11 (CAS CATO-C4X-314311)
- Doxorubicin Impurity 25 (CAS CATO-C4X-203325)
- Etoricoxib Impurity 7 (CAS CATO-C4X-10807)
- Methyl 5-amino-3-(trifluoromethyl)isoxazole-4-carboxylate (CAS 108655-61-4)
- 5-Ethyl-4-iodo-1-methyl-1H-pyrazole (CAS 1354705-15-9)
- 1-(2-Fluorobenzoyl)-3-methylpiperazine (CAS 1240567-73-0)
- (2-Butoxy-6-fluorophenyl)boronic acid (CAS 870777-19-8)
- 7-Iodoisoindolin-1-one (CAS 866766-96-3)
- 2-Chloro-1-[1-(4-ethoxyphenyl)-2,5-dimethyl-1h-pyrrol-3-yl]ethan-1-one (CAS 315710-86-2)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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