(6-Chloro-3-fluoropyridin-2-yl)methanamine CAS 1256804-79-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1256804-79-1
Molecular FormulaC6H6ClFN2
Molecular Weight160.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(6-Chloro-3-fluoropyridin-2-yl)methanamine CAS 1256804-79-1 chemical structure

Description

The occurrence of (6-Chloro-3-fluoropyridin-2-yl)methanamine is closely related to a nitrile group, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies (6-Chloro-3-fluoropyridin-2-yl)methanamine (CAS 1256804-79-1), a certified reference material (molecular formula C6H6ClFN2, MW 160.58 g/mol) for analytical method development and quality control.

The molecular framework of (6-Chloro-3-fluoropyridin-2-yl)methanamine (C6H6ClFN2) is characterized by a nitrile group, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (6-Chloro-3-fluoropyridin-2-yl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H6ClFN2
Molecular Weight160.58 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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