5-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile CAS 1256809-57-0
| CAS No. | 1256809-57-0 |
| Molecular Formula | C8H4FN3 |
| Molecular Weight | 161.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (CAS 1256809-57-0) is a high-purity analytical reference standard with the molecular formula C8H4FN3 and a molecular weight of 161.14 g/mol.
Based on its molecular formula C8H4FN3, 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 161.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4FN3 |
| Molecular Weight | 161.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- 4-Fluoro-1H-pyrrolo[2,3-c]pyridine-3-carbonitrile (CAS 1190311-97-7)
- 4-Fluoro-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile (CAS 1190313-36-0)
- 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile (CAS 1190316-08-5)
- 6-Fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 1190318-70-7)
- 6-Fluoro-1H-indazole-4-carbonitrile (CAS 1227270-90-7)
- 4-Fluoro-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile (CAS 1260381-44-9)
- 4-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (CAS 1260383-56-9)
- 5-Fluoro-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile (CAS 1260384-36-8)
Recommended Standards
- 8-Fluoroimidazo[1,2-a]pyridine-3-carbonitrile (CAS 1260657-34-8)
- 7-Fluoro-1H-indazole-3-carbonitrile (CAS 1352395-36-8)
- 6-Fluoroimidazo[1,2-a]pyridine-3-carbonitrile (CAS 1134327-96-0)
- 3-Fluoro-1H-pyrrolo[3,2-b]pyridine-5-carbonitrile (CAS 1352398-04-9)
- 2-[7-Chloro-2-(pyridin-2-yl)-1h-indol-3-yl]ethan-1-amine hydrochloride (CAS 1049783-68-7)
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