8-Bromoisoquinoline-1-carboxylic acid CAS 1256818-87-7
| CAS No. | 1256818-87-7 |
| Molecular Formula | C10H6BrNO2 |
| Molecular Weight | 252.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 8-Bromoisoquinoline-1-carboxylic acid (CAS 1256818-87-7), a certified reference material (molecular formula C10H6BrNO2, MW 252.06 g/mol) for analytical method development and quality control.
The molecular framework of 8-Bromoisoquinoline-1-carboxylic acid (C10H6BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 8-Bromoisoquinoline-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6BrNO2 |
| Molecular Weight | 252.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromoisoquinoline Standards
- Ethyl 5-Bromoisoquinoline-1-carboxylate (CAS 1111311-65-9)
- 4-Bromoisoquinoline-1-carboxylic acid (CAS 1179149-25-7)
- 5-Bromoisoquinoline-1-carboxylic acid (CAS 1253654-73-7)
- 6-Bromoisoquinoline-1-carboxylic Acid (CAS 1256806-36-6)
- 7-Bromoisoquinoline-1-carboxylic acid (CAS 1256833-95-0)
- 5-Bromoisoquinoline-4-carboxylic acid (CAS 1384251-84-6)
- 5-Bromoisoquinoline-3-carboxylic acid (CAS 1416712-83-8)
- 6-Bromoisoquinoline-3-carboxylic acid (CAS 1416713-22-8)
Recommended Standards
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- 5-Bromoquinoline-4-carboxylic acid (CAS 1219834-22-6)
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- 5-(4-(Dimethylamino)phenyl)-4,5-dihydroisoxazol-5-ol (CAS 53009-39-5)
- tert-Butyl 2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate (CAS 1839059-86-7)
- 2,2-Dichloro-3,3-dimethylbutane (CAS 594-84-3)
- 1334AF 3,5,7-Trimethyl-1H-indole-2-carboxylic acid 876715-82-1 C12H13NO2 (CAS 876715-82-1)
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