5-Bromoisoquinoline-4-carboxylic acid CAS 1384251-84-6
| CAS No. | 1384251-84-6 |
| Molecular Formula | C10H6BrNO2 |
| Molecular Weight | 252.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromoisoquinoline-4-carboxylic acid.
5-Bromoisoquinoline-4-carboxylic acid (CAS 1384251-84-6), molecular formula C10H6BrNO2 and molecular weight 252.06 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromoisoquinoline-4-carboxylic acid (C10H6BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromoisoquinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6BrNO2 |
| Molecular Weight | 252.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromoisoquinoline Standards
- Ethyl 5-Bromoisoquinoline-1-carboxylate (CAS 1111311-65-9)
- 4-Bromoisoquinoline-1-carboxylic acid (CAS 1179149-25-7)
- 5-Bromoisoquinoline-1-carboxylic acid (CAS 1253654-73-7)
- 6-Bromoisoquinoline-1-carboxylic Acid (CAS 1256806-36-6)
- 8-Bromoisoquinoline-1-carboxylic acid (CAS 1256818-87-7)
- 7-Bromoisoquinoline-1-carboxylic acid (CAS 1256833-95-0)
- 5-Bromoisoquinoline-3-carboxylic acid (CAS 1416712-83-8)
- 6-Bromoisoquinoline-3-carboxylic acid (CAS 1416713-22-8)
Recommended Standards
- 4-Bromoquinoline-7-carboxylic acid (CAS 1379367-77-7)
- 4-Bromoquinoline-8-carboxylic acid (CAS 1416438-29-3)
- 7-Bromo-6-hydroxyquinoline-5-carbaldehyde (CAS 1378260-81-1)
- 5-Bromoquinoline-3-carboxylic Acid (CAS 1416438-47-5)
- 2-Amino-4-chloro-5-fluorophenol (CAS 303181-72-8)
- 3-[3-(4-chlorophenyl)-4-formyl-1h-pyrazol-1-yl]propanenitrile (CAS 255710-84-0)
- (E)-1-(4-chlorobenzyl)-5,6-dimethyl-2-styryl-1H-benzo[d]imidazole (CAS 321433-08-3)
- Ethyl(4-fluorophenyl)sulfane (CAS 2924-75-6)
- Pitofenone Hydrochloride (CAS 1248-42-6)
- O-Pivaloylhydroxylamine (CAS 35657-34-2)
- 9-Hydroxy-4H-pyrimido[1,6-a]pyrimidin-4-one (CAS 123420-39-3)
- 2-(2,4-Difluoro-5-methylphenyl)acetonitrile (CAS 1242314-98-2)
- 3-azidopropyl methanesulfonate (CAS 105064-28-6)
- (Des-Gly2)-Exenatide trifluoroacetate salt (CAS 1678416-78-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com