Favipiravir Impurity 19 CAS 1257072-34-6
| CAS No. | 1257072-34-6 |
| Molecular Formula | C5HBrClN3 |
| Molecular Weight | 218.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Favipiravir Impurity 19 (CAS 1257072-34-6, C5HBrClN3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Favipiravir Impurity 19 (C5HBrClN3) is characterized by a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Favipiravir Impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5HBrClN3 |
| Molecular Weight | 218.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related Favipiravir Standards
- Favipiravir Impurity 23 (CAS 440124-25-4)
- Favipiravir Impurity 3 (CAS 259793-88-9)
- Favipiravir Impurity 17 (CAS 6329-74-4)
- Favipiravir Impurity 24 (CAS CATO-C4X-210224)
- Favipiravir Impurity 23 (CAS 356783-14-7)
- Favipiravir Impurity 24 (CAS 6966-01-4)
- Favipiravir Impurity 16 (CAS 1023813-21-9)
- Favipiravir Impurity 4 (CAS 259794-06-4)
Recommended Standards
- 1-Chloro-4-iodobutane (CAS 10297-05-9)
- 3-Bromo-6-chloropyrazine-2-carbonitrile (CAS 2180081-37-0)
- Azetidin-3-yl 2,2,2-trichloroacetate (CAS 1219956-76-9)
- 1,6-Bis(trimethylsilyl)hexa-1,3,5-triyne (CAS 21752-86-3)
- (S)-Baxdrostat Impurity 25 (CAS 1428652-36-1)
- Bifendate Impurity 8 (CAS CATO-C4X-25558)
- Dabigatran Impurity 120 (CAS CATO-C4X-1089120)
- (2-(Aminomethyl)phenyl)methanesulfonamide hydrochloride (CAS 33050-14-5)
- 2-{[1-(2-fluorophenyl)ethyl]amino}-3-methylbutan-1-ol hydrochloride (CAS 1803583-20-1)
- (R)-1-(2-Chloro-4-fluorophenyl)ethanamine hydrochloride (CAS 1391465-25-0)
- 4-Methyl-5-(4-(pyrrolidin-1-ylsulfonyl)phenyl)-4H-1,2,4-triazole-3-thiol (CAS 917561-74-1)
- 5-Bromo-1-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 1126779-29-0)
- 6-bromo-1H-indazole-3-carbonitrile (CAS 885278-24-0)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
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