(S)-Baxdrostat Impurity 25 CAS 1428652-36-1
| CAS No. | 1428652-36-1 |
| Molecular Formula | C22H25N3O3 |
| Molecular Weight | 379.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (S)-Baxdrostat Impurity 25 (CAS 1428652-36-1), a pharmacopoeial impurity reference standard (molecular formula C22H25N3O3, MW 379.46 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of (S)-Baxdrostat Impurity 25 (C22H25N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), (S)-Baxdrostat Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H25N3O3 |
| Molecular Weight | 379.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related S Standards
- Baxdrostat N-Oxide (CAS CATO-C4X-34341)
- Baxdrostat Impurity 20 (CAS 1428652-30-5)
- Baxdrostat Impurity 21 (CAS 1428652-31-6)
- Baxdrostat Impurity 22 (CAS 1428652-32-7)
- Baxdrostat Impurity 23 (CAS 1428652-33-8)
- (S)-Baxdrostat Impurity 24 (CAS 1428652-34-9)
- Baxdrostat Impurity 26 (CAS 1428652-35-0)
- Baxdrostat Impurity 5 (CAS 3062109-53-6)
Recommended Standards
- Sudan Red 7B (CAS 6368-72-5)
- 3-Benzyl-8-(butylsulfonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione (CAS 1021265-30-4)
- (S)-2-Amino-6-(5-(dimethylamino)naphthalene-1-sulfonamido)hexanoic acid (CAS 1101-84-4)
- Tert-butyl 3-(((1,1-dioxidobenzo[d]isothiazol-3(2H)-ylidene)amino)methyl)piperidine-1-carboxylate (CAS 1353958-84-5)
- Baloxavir Impurity 116 (CAS CATO-C4X-2108116)
- Sevoflurane EP Impurity A (CAS 58109-34-5)
- Milrinone Impurity 4 (CAS CATO-C4X-10914)
- 1-(2,5-Dimethyl-1-(thiazol-2-yl)-1H-pyrrol-3-yl)-2,2,2-trifluoroethan-1-one (CAS 866156-72-1)
- Pirenoxine Impurity 1 (CAS 41827-15-0)
- 2-Chloro-4,4’-bipyridine (CAS 53344-73-3)
- (4S,4'S)-2,2'-(Cycloheptane-1,1-diyl)bis(4-benzyl-4,5-dihydrooxazole) (CAS 2757082-25-8)
- 3'-(Benzyloxy)-[1,1'-biphenyl]-4-amine (CAS 400749-48-6)
- N1,N2-bis(4-methoxyphenyl)oxalamide (CAS 3299-63-6)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
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