6-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1-amine CAS 1257378-82-7
| CAS No. | 1257378-82-7 |
| Molecular Formula | C15H18BFN2O2 |
| Molecular Weight | 288.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1-amine.
6-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1-amine (CAS 1257378-82-7), molecular formula C15H18BFN2O2 and molecular weight 288.13 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C15H18BFN2O2, 6-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1-amine contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 288.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H18BFN2O2 |
| Molecular Weight | 288.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 1-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-ol (CAS 2638502-42-6)
- 6-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-ol (CAS 2667057-65-8)
- 7-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-ol (CAS 2773311-37-6)
- 1-Fluoro-3-(4-iodophenyl)bicyclo[1.1.1]Pentane (CAS 1934526-34-7)
- 1-(3-Fluoro-benzyl)-piperidine-3-carboxylic acid (CAS 1042911-09-0)
- 7-Fluoro-6-iodoisoquinolin-3-amine (CAS 2409844-29-5)
- 4-Fluoro-5-Oxo-2,4-Bis(Trifluoromethyl)-1,3-Dioxolane-2-Carbonyl Fluoride (CAS 7345-49-5)
- 4-(2-Fluoro-4-nitrophenoxy)-5-methyl-5H-pyrrolo[3,2-d]pyrimidine (CAS 875339-19-8)
Recommended Standards
- 4-Iodo-2-(1-piperidinyl)pyridine (CAS 1239969-35-7)
- 2-(3,4-dichlorophenyl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid (CAS 1267413-08-0)
- 1-(2,4-DIchloro-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl ester (CAS 1239769-46-0)
- 1-(Cyclopent-3-en-1-yl)-4-iodo-3,5-dimethyl-1H-pyrazole (CAS 1350323-36-2)
- 4-amino-N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-5-yl]butanamide (CAS 2421217-06-1)
- Ethyl 3-(2-(1H-indol-1-yl)ethyl)-2-oxopiperidine-3-carboxylate (CAS 833436-57-0)
- 5-Fluoro-N-methylbenzo[b]thiophene-2-carboxamide (CAS 1089580-14-2)
- n-(1,3-Dihydroxypropan-2-yl)formamide (CAS 1490044-36-4)
- Varenicline Impurity 46 (CAS CATO-C4X-196246)
- 6-Cyclopropyl-2-hydroxy-4-methylnicotinonitrile (CAS 1346576-02-0)
- Methyl 1,7-dimethyl-1H-indole-3-carbimidate (CAS 760911-42-0)
- 3,5-Dimethyl-4-(tributylstannyl)isoxazole (CAS 136295-80-2)
- tert-Butyl 2-hydroxy-7-azaspiro[3.6]decane-7-carboxylate (CAS 1445951-30-3)
- Peptide-GMF (CAS CATO-CPTD788469)
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