6-Chloro-5-fluoro-2-(pyrazin-2-yl)-1H-benzo[d]imidazole CAS 1257535-23-1
| CAS No. | 1257535-23-1 |
| Molecular Formula | C11H6ClFN4 |
| Molecular Weight | 248.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Chloro-5-fluoro-2-(pyrazin-2-yl)-1H-benzo[d]imidazole (CAS 1257535-23-1), molecular formula C11H6ClFN4 and molecular weight 248.64 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Chloro-5-fluoro-2-(pyrazin-2-yl)-1H-benzo[d]imidazole (C11H6ClFN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 248.64 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 6-Chloro-5-fluoro-2-(pyrazin-2-yl)-1H-benzo[d]imidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H6ClFN4 |
| Molecular Weight | 248.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094260-22-6)
- 6-Chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094354-48-9)
- 6-Chloro-3-(3-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094425-19-0)
- 3-Chloro-6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1116743-29-3)
- 2-(2-Chloro-4-fluorophenoxy)nicotinonitrile (CAS 1183594-45-7)
- 5-Chloro-2-(2-fluorophenyl)oxazolo[5,4-b]pyridine (CAS 126921-80-0)
- 4-Chloro-1-(3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1269702-96-6)
- 6-Chloro-2-(4-fluorophenyl)oxazolo[5,4-b]pyridine (CAS 1354749-65-7)
Recommended Standards
- (2Z)-2-Amino-3-[(E)-[(2-chloro-6-fluorophenyl)methylidene]amino]but-2-enedinitrile (CAS 117691-67-5)
- 3-Oxo-2H,3H,4H-pyrido[3,2-b][1,4]oxazine-7-sulfonyl chloride (CAS 1116135-67-1)
- 5-Chloro-2-(3-fluorophenyl)oxazolo[5,4-b]pyridine (CAS 1422198-83-1)
- 5-Chloro-2-(4-fluorophenyl)oxazolo[5,4-b]pyridine (CAS 1422198-87-5)
- 1-Aminomethyl-cyclopropylamine dihydrochloride (CAS 849149-67-3)
- N,4-dimethyl-1-phenylpentan-1-amine (CAS 912907-08-5)
- 3-Methoxy-2-methylacetanilide (CAS 50868-74-1)
- Posaconazole Impurity 76 (CAS CATO-C4X-120876)
- Tri(cyclohexa-2,5-dien-1-yl)silane (CAS 1807776-35-7)
- 7-Aminobenzofuran Hydrochloride (CAS 115464-83-0)
- Etrasimod Impurity 46 (CAS CATO-C4X-321446)
- 4-(Bromomethyl)-2,4-dimethylhexane (CAS 1490609-10-3)
- 1-Butanethiol (CAS 109-79-5)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
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