3-(4-Hydroxyphenyl)picolinic acid CAS 1258622-77-3
| CAS No. | 1258622-77-3 |
| Molecular Formula | C12H9NO3 |
| Molecular Weight | 215.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-(4-Hydroxyphenyl)picolinic acid (CAS 1258622-77-3), molecular formula C12H9NO3 and molecular weight 215.20 g/mol, is a CATO reference standard with documented purity and traceability.
3-(4-Hydroxyphenyl)picolinic acid (C12H9NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9NO3 |
| Molecular Weight | 215.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Related Hydroxyphenyl Standards
- 6-(2-Hydroxyphenyl)nicotinic acid (CAS 1033845-00-9)
- 5-(3-Hydroxyphenyl)nicotinic acid (CAS 1181452-05-0)
- 5-(4-Hydroxyphenyl)nicotinic acid (CAS 1181566-40-4)
- 5-(2-Hydroxyphenyl)nicotinic acid (CAS 1258609-83-4)
- 3-(2-Hydroxyphenyl)picolinic acid (CAS 1258618-22-2)
- 3-(4-Hydroxyphenyl)isonicotinic acid (CAS 1258625-94-3)
- 2-(2-Hydroxyphenyl)isonicotinic acid (CAS 1258626-16-2)
- 2-(4-Hydroxyphenyl)isonicotinic acid (CAS 1258626-91-3)
Recommended Standards
- Tert-butyl (S)-4-methyl-2,5-dioxooxazolidine-3-carboxylate (CAS 125814-30-4)
- (E)-Methyl 4-(4-cyanophenyl)-2-oxobut-3-enoate (CAS 1257520-11-8)
- 2-(3-Hydroxyphenyl)isonicotinic acid (CAS 1258629-11-6)
- n-(4-(Difluoromethoxy)benzyl)acetamide (CAS 1252445-47-8)
- 1-(1h-Indazole-5-carbonyl)piperidine-4-carboxylic acid (CAS 1099083-58-5)
- 2-(5-Methyl-1H-pyrazol-3-yl)acetic acid hydrochloride (CAS 1103508-20-8)
- N-(Benzo[d]thiazol-2-yl)-5-(4-fluorophenyl)oxazole-2-carboxamide (CAS 955700-45-5)
- (3-Chloro-5-fluoropyridin-4-yl)methanol (CAS 1227496-03-8)
- 1-Tetradecylpyridin-1-ium Chloride Hydrate (CAS CATO-C3D-26089)
- Methyl 3-(Cyclopropylamino)-4-nitrobenzoate (CAS 1912589-06-0)
- 6-Amino-1-(4-chlorophenyl)pyrimidine-2,4(1H,3H)-dione (CAS 60664-00-8)
- 2,6-Dimethylhept-6-en-2-ol (CAS 32779-58-1)
- Dimethylmyleran (CAS 55-93-6)
- Glucagon receptor antagonist I (CAS 438618-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com