(3-Chloro-5-fluoropyridin-4-yl)methanol CAS 1227496-03-8
| CAS No. | 1227496-03-8 |
| Molecular Formula | C6H5ClFNO |
| Molecular Weight | 161.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (3-Chloro-5-fluoropyridin-4-yl)methanol.
(3-Chloro-5-fluoropyridin-4-yl)methanol (CAS 1227496-03-8) is a high-purity analytical reference standard with the molecular formula C6H5ClFNO and a molecular weight of 161.56 g/mol.
Based on its molecular formula C6H5ClFNO, (3-Chloro-5-fluoropyridin-4-yl)methanol contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 161.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (3-Chloro-5-fluoropyridin-4-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5ClFNO |
| Molecular Weight | 161.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-5-fluoro-3-methoxypyridine (CAS 1097264-89-5)
- 4-Chloro-3-fluoropyridine-2-methanol (CAS 113209-83-9)
- 4-Chloro-5-fluoro-2-methylpyridine, N-oxide (CAS 113209-89-5)
- 4-Chloro-5-fluoro-2-pyridinemethanol (CAS 113209-90-8)
- 3-Chloro-2-fluoro-4-(hydroxymethyl)pyridine (CAS 1149587-00-7)
- (6-Chloro-5-fluoropyridin-3-yl)methanol (CAS 1174028-24-0)
- 2-Chloro-3-fluoro-4-methoxypyridine (CAS 1184172-10-8)
- 2-Chloro-5-fluoro-4-methoxypyridine (CAS 1211515-16-0)
Recommended Standards
- (6-Chloro-5-fluoropyridin-2-yl)methanol (CAS 1227493-54-0)
- 2-Chloro-4-fluoro-6-methoxypyridine (CAS 1227502-57-9)
- (5-Chloro-6-fluoropyridin-3-yl)methanol (CAS 1217554-18-1)
- 4-Chloro-2-fluoro-5-methoxypyridine (CAS 1227502-63-7)
- 1,1,2-Tribromo-1-(nonafluorobutyl)ethane (CAS 59665-24-6)
- 4-(4-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (CAS 360791-49-7)
- 3-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyridine (CAS 1214356-58-7)
- 5-((4-Amino-2-fluorophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione (CAS 1035556-26-3)
- (S)-4-(1-aminopropan-2-yl)benzonitrile (CAS 2374976-88-0)
- N1-(2-Chlorophenyl)-N1-methylbenzene-1,2-diamine (CAS 1207629-88-6)
- 5,6,7-Trimethoxy-4-methyl-2H-chromen-2-one (CAS 7679-43-8)
- 4-Chloro-2-(1-phenylethyl)phenol (CAS 5828-70-6)
- 7-Methoxy-3-(piperidin-1-yl)isoquinoline-5,8-dione (CAS 54753-69-4)
- Semaglutide impurity 61 (CAS CATO-C4X-222661)
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