N-(8-bromo-4-oxo-3,4-dihydroquinazolin-2-yl)acetamide CAS 1258630-87-3
| CAS No. | 1258630-87-3 |
| Molecular Formula | C10H8BrN3O2 |
| Molecular Weight | 282.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 282.09 g/mol gives N-(8-bromo-4-oxo-3,4-dihydroquinazolin-2-yl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N-(8-bromo-4-oxo-3,4-dihydroquinazolin-2-yl)acetamide (CAS 1258630-87-3), a certified reference material (molecular formula C10H8BrN3O2, MW 282.09 g/mol) for analytical method development and quality control.
The molecular framework of N-(8-bromo-4-oxo-3,4-dihydroquinazolin-2-yl)acetamide (C10H8BrN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8BrN3O2 |
| Molecular Weight | 282.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 4-Bromo-8-methoxyquinoline-2-carboxylic acid (CAS 103862-09-5)
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- 6-Bromo-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 1120249-21-9)
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- 2-(6-Bromo-4-oxoquinolin-1(4H)-yl)acetic acid (CAS 1216901-25-5)
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- 4-Bromo-N-(3-methyl-1,2,4-oxadiazol-5-yl)benzamide (CAS 1222988-84-2)
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Recommended Standards
- Methyl 7-bromo-2-oxo-1,2-dihydroquinoline-5-carboxylate (CAS 1253105-80-4)
- Methyl 5-bromo-3-(1H-pyrrol-1-yl)pyrazine-2-carboxylate (CAS 1260871-28-0)
- 1-[(2-Bromophenyl)methyl]-4-nitro-1h-pyrazole (CAS 1240568-81-3)
- Methyl 4-bromo-1-oxo-1,2-dihydroisoquinoline-7-carboxylate (CAS 1264209-67-7)
- N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}acetamide (CAS 477853-88-6)
- [S(R)]-N-[(R)-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]phenylmethyl]-N,2-dimethyl-2-propanesulfinamide (CAS 2757083-09-1)
- Benzyl 2-oxo-6-azaspiro[3.4]octane-6-carboxylate (CAS 1440961-75-0)
- 1-(6-(2-Chloroacetyl)-1H-indol-1-yl)-2,2-dimethylpropan-1-one (CAS 116621-13-7)
- Pramipexole Impurity 70 (CAS 1373869-90-9)
- 7170JZ1QF3 3317-61-1 5,5-Dimethyl-1-pyrroline-1-oxide DMPO 3,4-Dihydro-2,2-dimethyl-2H-pyrrole 1-oxide 2H-Pyrrole, 3,4-dihydro-2,2-dimethyl-, 1-oxide 5,5-Dimethyl-1-pyrrolidin-1-oxide 5,5-Dimethyl-1-pyrroline N-oxide 5,5-Dimethylpyrroline-N-oxide EINECS 222-011-1 UNII-7170JZ1QF3 (CAS 3317-61-1)
- methyl 1-bromo-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate (CAS 1455091-21-0)
- Timolol Impurity 24 (CAS CATO-C4X-149624)
- 1-[Chloro(difluoro)methoxy]-3-(trifluoromethyl)benzene (CAS 1417566-68-7)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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