8-Bromo-4-(4-methylpiperazin-1-yl)quinazolin-2-amine CAS 1258630-98-6
| CAS No. | 1258630-98-6 |
| Molecular Formula | C13H16BrN5 |
| Molecular Weight | 322.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Bromo-4-(4-methylpiperazin-1-yl)quinazolin-2-amine (CAS 1258630-98-6), molecular formula C13H16BrN5 and molecular weight 322.20 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution, 8-Bromo-4-(4-methylpiperazin-1-yl)quinazolin-2-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 322.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Bromo-4-(4-methylpiperazin-1-yl)quinazolin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16BrN5 |
| Molecular Weight | 322.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
Related Bromo Standards
- 3-Bromo-7-(4-methoxybenzyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine (CAS 1075728-85-6)
- 4-Bromo-9-phenyl-9H-carbazole (CAS 1097884-37-1)
- 3-Bromo-9-phenylcarbazole (CAS 1153-85-1)
- 4-Bromo-2-(((2-methoxybenzyl)amino)methyl)phenol (CAS 1232796-50-7)
- 3-Bromo-6-phenyl-9H-carbazole (CAS 1303472-72-1)
- (5-Bromo-2-{methyl[2-(pyridin-2-yl)ethyl]amino}pyridin-3-yl)methanol (CAS 1306607-07-7)
- 1-Bromo-9-phenyl-9H-carbazole (CAS 1333002-37-1)
- Ethyl 4-bromo-8-isopropylquinoline-3-carboxylate (CAS 1378255-52-7)
Recommended Standards
- 4-(Difluoromethoxy)-3-fluoro-3'-(trifluoromethoxy)-1,1'-biphenyl (CAS 1261611-39-5)
- (4-(Benzyloxy)-3-bromo-5-methoxyphenyl)methanamine (CAS 1154001-51-0)
- 2-(Difluoromethoxy)-4-fluoro-2'-(trifluoromethoxy)biphenyl (CAS 1261649-98-2)
- 2-(Difluoromethoxy)-5-fluoro-4'-(trifluoromethoxy)biphenyl (CAS 1261797-16-3)
- N,N-Diethyl-1-(pyrrolidin-3-yl)-1H-1,2,3-triazole-4-carboxamide (CAS 1707399-35-6)
- Ethyl 2-amino-5,6-dihydro-4H-cyclopenta[d]thiazole-4-carboxylate, 97% (CAS 1019108-35-0)
- 7-Fluoro-1H-indole-4-carboxylic acid (CAS 588688-52-2)
- 3-(Chloromethyl)benzofuran (CAS 67713-99-9)
- rel-(2S,3R)-Methyl 2-chloro-3-methoxybutanoate (CAS 26839-90-7)
- 1-(3-(Furan-2-yl)-5-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)propan-1-one (CAS 1448122-75-5)
- Elastatinal (CAS 51798-45-9)
- Ac-Tyr-Lys-NH? trifluoroacetate salt (CAS 270597-64-3)
- Methyl (S)-3-amino-2-methylpropanoate hydrochloride (CAS 168828-17-9)
- D-[Ser]11-Semaglutide (CAS CATO-CPTD788629)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com