tert-butyl 4-(2-ethoxy-1,1-difluoro-2-oxo-ethyl)piperidine-1-carboxylate CAS 1258639-00-7
| CAS No. | 1258639-00-7 |
| Molecular Formula | C14H23F2NO4 |
| Molecular Weight | 307.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-butyl 4-(2-ethoxy-1,1-difluoro-2-oxo-ethyl)piperidine-1-carboxylate (CAS 1258639-00-7), molecular formula C14H23F2NO4 and molecular weight 307.33 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, tert-butyl 4-(2-ethoxy-1,1-difluoro-2-oxo-ethyl)piperidine-1-carboxylate is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 307.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H23F2NO4 |
| Molecular Weight | 307.33 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)amino)pyridine-3-sulfonamide (CAS 1251688-40-0)
- (S)-2-((tert-butoxycarbonyl)amino)-3-(4,4-difluorocyclohexyl)propanoic acid (CAS 1311203-16-3)
- 3-Amino-6-(4-methanesulfonylphenyl)pyrazine-2-carboxylic acid methyl ester (CAS 1232423-27-6)
- 2-(Pyridin-3-ylamino)naphtho[2,3-d]thiazole-4,9-dione (CAS 1313739-00-2)
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- 2-(2-(3-Chloro-2-fluorophenoxy)ethyl)-1,3-dioxane (CAS 1443336-74-0)
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- (1-Mesitylethyl)hydrazine (CAS 1016498-75-1)
- Isonicotinamide, 2-chloro- (CAS 100859-84-5)
- 3-Methylquinolin-4(1H)-one (CAS 72553-74-3)
- 5-Bromo-1,4-difluoro-2-isopropoxybenzene (CAS 2121514-69-8)
- Methyl 2,2-difluoro-2-(4-methoxyphenyl)acetate (CAS 1393539-93-9)
- Methyl n-Octyl Sulfide (CAS 3698-95-1)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
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