6-(Difluoromethyl)-3-azabicyclo[4.1.0]heptane CAS 1258650-06-4
| CAS No. | 1258650-06-4 |
| Molecular Formula | C7H11F2N |
| Molecular Weight | 147.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-(Difluoromethyl)-3-azabicyclo[4.1.0]heptane is closely related to a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-(Difluoromethyl)-3-azabicyclo[4.1.0]heptane (CAS 1258650-06-4) is a high-purity analytical reference standard with the molecular formula C7H11F2N and a molecular weight of 147.17 g/mol.
The molecular framework of 6-(Difluoromethyl)-3-azabicyclo[4.1.0]heptane (C7H11F2N) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H11F2N |
| Molecular Weight | 147.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 6-(Difluoromethyl)-1-azaspiro[3.3]heptane (CAS 2287275-28-7)
- 1-(Difluoromethyl)-3-methyl-1H-pyrazol-4-amine (CAS 1201935-88-7)
- 1-(Difluoromethyl)-5-methyl-1h-pyrazol-4-amine (CAS 1245772-66-0)
- 3-(Difluoromethyl)-1-methyl-1H-pyrazol-5-amine (CAS 1245806-69-2)
- 5-(difluoromethyl)-3-ethyl-1H-1,2,4-triazole (CAS 1247413-25-7)
- 1-(Difluoromethyl)-4-methyl-1h-pyrazol-3-amine (CAS 1340566-75-7)
- [1-(difluoromethyl)-1h-pyrazol-4-yl]methanamine (CAS 1365942-99-9)
- (5-(Difluoromethyl)-1h-pyrazol-4-yl)methanamine (CAS 1461869-02-2)
Recommended Standards
- 5-Cyclopropylpicolinaldehyde (CAS 1256825-21-4)
- 1-(6-Vinylpyridin-3-yl)ethanone (CAS 1259929-69-5)
- 4-Cyclopropylnicotinaldehyde (CAS 1256793-54-0)
- 3-(Hydroxymethyl)-2-methylbenzonitrile (CAS 1260024-34-7)
- 2-((4-(2-Chlorophenyl)-6-(4-chlorophenyl)-3-cyanopyridin-2-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide (CAS 332372-39-1)
- 6-Chloro-2-methyl-3-vinylpyridine (CAS 1355205-23-0)
- Methyl 2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-6'-carboxylate (CAS 1203682-98-7)
- Tert-butyl 4-(4-((methylamino)methyl)phenyl)piperidine-1-carboxylate (CAS 1853217-55-6)
- 1-Benzyl-4-(3,4-dimethoxyphenyl)-1,2,3,6-tetrahydropyridine (CAS 66970-77-2)
- Epalrestat impurity 38 (CAS CATO-C4X-223638)
- 6-Bromo-5-fluoro-1H-indazole-3-carbaldehyde (CAS 1352394-47-8)
- 1-(2,6-Dichloro-4-(trifluoromethyl)phenyl)-5-ethoxy-4-nitro-1H-pyrazole (CAS 113802-83-8)
- N-(cyanomethyl)-2-(thiophen-2-yl)acetamide (CAS 349424-08-4)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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