6-Fluoropyridine-3-sulfonyl fluoride CAS 1259065-58-1
| CAS No. | 1259065-58-1 |
| Molecular Formula | C5H3F2NO2S |
| Molecular Weight | 179.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Fluoropyridine-3-sulfonyl fluoride (CAS 1259065-58-1) is a high-purity analytical reference standard with the molecular formula C5H3F2NO2S and a molecular weight of 179.14 g/mol.
The molecular framework of 6-Fluoropyridine-3-sulfonyl fluoride (C5H3F2NO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Fluoropyridine-3-sulfonyl fluoride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3F2NO2S |
| Molecular Weight | 179.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluoropyridine Standards
- 5-Fluoropyridine-2-sulfonyl fluoride (CAS 1210867-93-8)
- 1,1'-(4-fluoropyridine-2,6-diyl)bis(ethan-1-one) (CAS 1393576-72-1)
- 6-Fluoropyridine-2-sulfonamide (CAS 124433-70-1)
- 5-Fluoropyridine-3-sulfonamide (CAS 1247591-65-6)
- 2-Fluoropyridine-3-sulfonamide (CAS 1260427-18-6)
- 2-Fluoropyridine-4-sulfonamide (CAS 2357160-67-7)
- 5-fluoropyridine-2-sulfonamide (CAS 1250674-08-8)
- 3-fluoropyridine-2-sulfonamide (CAS 133120-15-7)
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