(1-(2,2,2-Trifluoroethyl)-1h-imidazol-2-yl)methanamine CAS 1251925-35-5
| CAS No. | 1251925-35-5 |
| Molecular Formula | C6H8F3N3 |
| Molecular Weight | 179.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies (1-(2,2,2-Trifluoroethyl)-1h-imidazol-2-yl)methanamine (CAS 1251925-35-5), a certified reference material (molecular formula C6H8F3N3, MW 179.14 g/mol) for analytical method development and quality control.
The molecular framework of (1-(2,2,2-Trifluoroethyl)-1h-imidazol-2-yl)methanamine (C6H8F3N3) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8F3N3 |
| Molecular Weight | 179.14 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoroethyl Standards
- 3-Methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-amine (CAS 1006448-59-4)
- 5-Methyl-1-(2,2,2-trifluoroethyl)-1h-pyrazol-3-amine (CAS 1006486-85-6)
- 3-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-amine (CAS 1174850-85-1)
- 4-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-3-amine (CAS 1174876-14-2)
- 3-ethyl-5-(2,2,2-trifluoroethyl)-1H-1,2,4-triazole (CAS 1248135-05-8)
- (1-(2,2,2-Trifluoroethyl)-1H-pyrazol-3-yl)methanamine (CAS 1328640-50-1)
- [1-(2,2,2-trifluoroethyl)-1h-pyrazol-5-yl]methanamine (CAS 1328640-83-0)
- 5-Methyl-1-(2,2,2-trifluoroethyl)-1h-pyrazol-4-amine (CAS 1374829-59-0)
Recommended Standards
- 2,2,2-Trifluoro-1-(5-methylfuran-2-yl)ethan-1-amine (CAS 1250563-61-1)
- 6-Fluoropyridine-3-sulfonyl fluoride (CAS 1259065-58-1)
- 1-(3-(Trifluoromethyl)-1h-pyrazol-4-yl)ethan-1-amine (CAS 1248551-15-6)
- 2-(3-(Trifluoromethyl)-1H-pyrazol-4-yl)ethanamine (CAS 1314904-42-1)
- 2-(Pyridyldithio)ethylamine (hydrochloride) (CAS 106139-15-5)
- 2-(Dibenzo[b,d]furan-2-yloxy)ethan-1-amine (CAS 1011407-19-4)
- 1,5-Dimethyl-6H-pyrido[4,3-b]carbazole 2-hydroxypropanoate (CAS 76201-88-2)
- (2-Chlorophenyl)(4-nitrophenyl)methanone (CAS 77778-73-5)
- tert-Butyl (1-oxoheptan-3-yl)carbamate (CAS 1455442-30-4)
- 2-(3,4-Dimethoxybenzoyl)-6-methylpyridine (CAS 31749-14-1)
- 3-(4-Ethyl-5-((3-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 577696-07-2)
- 4-(2-Bromophenyl)-4-oxobutanenitrile (CAS 884504-61-4)
- 4-(Bromomethyl)oxetan-2-one (CAS 33282-42-7)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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