(Rac)-Tofacitinib CAS 1259404-17-5
| CAS No. | 1259404-17-5 |
| Molecular Formula | C16H20N6O |
| Molecular Weight | 312.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (Rac)-Tofacitinib (CAS 1259404-17-5), a certified reference material (molecular formula C16H20N6O, MW 312.37 g/mol) for analytical method development and quality control.
(Rac)-Tofacitinib (C16H20N6O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H20N6O |
| Molecular Weight | 312.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 6 |
Related Rac Standards
- Tofacitinib Impurity 1 (CAS 1092578-46-5)
- Tofacitinib Impurity 2 (CAS 1092578-48-7)
- Tofacitinib Impurity 20 (CAS 1092578-43-2)
- Tofacitinib Impurity 245 (CAS CATO-C4X-1079245)
- Tofacitinib Impurity 3 (CAS 1092578-47-6)
- Tofacitinib Impurity 34 (Mixture of Diastereomers) (CAS 344418-92-4)
- Tofacitinib Base (CAS 477600-75-2)
- Tofacitinib Impurity 236 (CAS CATO-C4X-1079236)
Recommended Standards
- 5-(1-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethyl)-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 1254926-79-8)
- 2-(4-Aminophenyl)-4-phenylquinazolin-6-amine (CAS 128889-33-8)
- (2-Methoxypyrimidin-5-yl)(4-(p-tolyl)piperazin-1-yl)methanone (CAS 1251624-19-7)
- tert-Butyl 5'H-spiro[azetidine-3,6'-pyrido[3,2-e]pyrrolo[1,2-a]pyrazine]-1-carboxylate (CAS 1290627-64-3)
- N-Methyl-2-(1-naphthyloxy)-1-ethanamine hydrochloride (CAS 199453-86-6)
- N-Desacetyl 3-Demethyl Thiocolchicine (CAS 97043-09-9)
- 2-((2-Methyl-7-(trifluoromethyl)quinolin-4-yl)thio)acetic acid (CAS 1208785-74-3)
- 2-[(3AR)-1-(benzenesulfonyl)-3a-methyl-5-oxo-octahydropyrrolo[2,3-b]pyrrol-2-yl]phenyl benzenesulfonate (CAS 957029-95-7)
- 4-(4-(Dimethylamino)phenyl)-7,7-dimethyl-4,6,7,8-tetrahydro-2H-chromene-2,5(3H)-dione (CAS 338778-01-1)
- (1R,3R)-3-fluoro-3-methylcyclohexan-1-ol (CAS 1932614-99-7)
- 7-(Pyridazin-3-yl)-1,7-diazaspiro[4.4]nonane (CAS 646056-09-9)
- 2-(3,4,5-Trifluorobenzoyl)oxazole (CAS 898784-54-8)
- 4-Nitro-2-(trifluoromethyl)benzo[d]oxazole (CAS 573759-00-9)
- Adrenal Peptide E, bovine (CAS 78355-50-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com