Tofacitinib Impurity 245 CAS CATO-C4X-1079245

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1079245
Molecular FormulaC16H20N6O
Molecular Weight312.37 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tofacitinib Impurity 245 CAS CATO-C4X-1079245 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 312.37 g/mol gives Tofacitinib Impurity 245 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Tofacitinib Impurity 245 (CAS CATO-C4X-1079245), a pharmacopoeial impurity reference standard (molecular formula C16H20N6O, MW 312.37 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C16H20N6O, Tofacitinib Impurity 245 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 312.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Tofacitinib Impurity 245 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H20N6O
Molecular Weight312.37 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms6

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