N-Fmoc-L-Phe(3-OCF3)-OH CAS 1260592-32-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1260592-32-2
Molecular FormulaC25H20F3NO5
Molecular Weight471.43 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-Fmoc-L-Phe(3-OCF3)-OH CAS 1260592-32-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 471.43 g/mol gives N-Fmoc-L-Phe(3-OCF3)-OH distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-Fmoc-L-Phe(3-OCF3)-OH (CAS 1260592-32-2) is a high-purity analytical reference standard with the molecular formula C25H20F3NO5 and a molecular weight of 471.43 g/mol.

The molecular framework of N-Fmoc-L-Phe(3-OCF3)-OH (C25H20F3NO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-Fmoc-L-Phe(3-OCF3)-OH meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC25H20F3NO5
Molecular Weight471.43 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms1

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