(R)-Fmoc-2-amino-3-(2-tert-butoxycarbonyl-ethylsulfanyl)-propionic acid CAS 685863-48-3
| CAS No. | 685863-48-3 |
| Molecular Formula | C25H29NO6S |
| Molecular Weight | 471.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-Fmoc-2-amino-3-(2-tert-butoxycarbonyl-ethylsulfanyl)-propionic acid.
(R)-Fmoc-2-amino-3-(2-tert-butoxycarbonyl-ethylsulfanyl)-propionic acid (CAS 685863-48-3), molecular formula C25H29NO6S and molecular weight 471.57 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (R)-Fmoc-2-amino-3-(2-tert-butoxycarbonyl-ethylsulfanyl)-propionic acid (C25H29NO6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (R)-Fmoc-2-amino-3-(2-tert-butoxycarbonyl-ethylsulfanyl)-propionic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H29NO6S |
| Molecular Weight | 471.57 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related R Standards
- N-Fmoc-L-Phe(3-OCF3)-OH (CAS 1260592-32-2)
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- Fmoc-Tyr(3,5-Cl2)-OH (CAS 1391508-43-2)
- Fmoc-β-Ala-(α-Me)-L-Phe-OH (CAS CATO-CPTD788994)
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Recommended Standards
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- (S)-3-Isopropyl-5-(4-(1-((5-(4-(methylsulfonyl)phenyl)pyrazin-2-yl)oxy)ethyl)piperidin-1-yl)-1,2,4-oxadiazole (CAS 1032824-43-3)
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- 2H-Dithieno[3,2-e:2′,3′-g]benzotriazole10,13-dithia-3,4,5-triazatetracyclo[10.3.0.0²,⁶.0⁷,¹¹]pentadeca-1(12),2,5,7(11),8,14-hexaene (CAS 1415761-30-6)
- 3,5-Diiodo Thyroaldehyde (CAS 2828-49-1)
- 4-(Allylamino)-2,6-diphenylpyrimidine-5-carbonitrile (CAS 320418-31-3)
- 1-(5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl)ethan-1-amine hydrochloride (CAS 2126162-84-1)
- N,N,3-Trimethyl-5,6,7,8-tetrahydroquinoline-8-carbothioamide (CAS 53400-71-8)
- n-(4-Phenylbutan-2-yl)cyclopropanamine (CAS 953907-62-5)
- {3-bromo-4H,6H,7H,8H-pyrazolo[3,2-c][1,4]oxazepin-7-yl}methanol (CAS 1250999-61-1)
- 1,3-dibenzyl-1,3-dihydro-2H-1,3-benzimidazol-2-one (CAS 59103-39-8)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
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