Fmoc-(R)-3-Amino-3-(3,4-Difluorophenyl)-propionic acid CAS 1260601-05-5
| CAS No. | 1260601-05-5 |
| Molecular Formula | C24H19F2NO4 |
| Molecular Weight | 423.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Fmoc-(R)-3-Amino-3-(3,4-Difluorophenyl)-propionic acid (CAS 1260601-05-5) is a high-purity analytical reference standard with the molecular formula C24H19F2NO4 and a molecular weight of 423.41 g/mol.
Fmoc-(R)-3-Amino-3-(3,4-Difluorophenyl)-propionic acid (C24H19F2NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H19F2NO4 |
| Molecular Weight | 423.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fmoc Standards
- N-Fmoc-2,5-difluoro-L-phenylalanine (CAS 1004959-90-3)
- (S)-2-(Fmoc-amino)-3-(2,4-difluorophenyl)propanoic Acid (CAS 1032337-49-7)
- Fmoc-(S)-3-Amino-3-(3,4-Difluorophenyl)-propionic acid (CAS 1260596-69-7)
- Fmoc-(S)-3-Amino-3-(2,4-Difluorophenyl)-propionic acid (CAS 1260601-06-6)
- Fmoc-(R)-3-Amino-3-(2,4-Difluorophenyl)-propionic acid (CAS 1260614-57-0)
- Fmoc-3,4-difluoro-L-phenylalanine (CAS 198560-43-9)
- FMOC-D-3,4-Difluorophenylalanine (CAS 198545-59-4)
- N-Fmoc-3,5-difluoro-L-phenylalanine (CAS 205526-24-5)
Recommended Standards
- (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,5-difluorophenyl)propanoic acid (CAS 1260593-16-5)
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-difluorophenyl)propanoic acid (CAS 1260605-29-5)
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,5-difluorophenyl)propanoic acid (CAS 1260592-30-0)
- (2s)-3-(2,3-Difluorophenyl)-2-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid (CAS 1260605-30-8)
- 2-Ethynyl-5-isopropylthiophene (CAS 2304404-81-5)
- 1-(4-bromo-2-methylphenyl)-1H-pyrazole (CAS 1379371-45-5)
- Prop-2-yn-1-yl 3-chloro-4-((4-fluorobenzyl)oxy)benzoate (CAS 1706457-63-7)
- Trifarotene Impurity N56 (CAS 895543-00-7)
- 2-Oxiranemethanaminium, N,N-dimethyl-N-[2-[(2-methyl-1-oxo-2-propen-1-yl)oxy]ethyl]-, chloride , polymer with methyl 2-propenoate (CAS 65859-28-1)
- Benzyl (2R,5S)-5-amino-2-ethylpiperidine-1-carboxylate (CAS 2382381-33-9)
- tert-Butyl 4-(5-(4-(trifluoromethyl)phenyl)isoxazol-3-yl)piperidine-1-carboxylate (CAS 1033194-50-1)
- 2-(1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-imidazol-4-yl)acetic acid (CAS 29605-99-0)
- Lenalidomide Impurity 37 (CAS 1063995-54-9)
- Antifreeze Polypeptide 6 (winter flounder) trifluoroacetate salt (CAS 122604-16-4)
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