6-Bromo-8-fluoroimidazo[1,2-a]pyridine-3-carbonitrile CAS 1260657-25-7
| CAS No. | 1260657-25-7 |
| Molecular Formula | C8H3BrFN3 |
| Molecular Weight | 240.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Bromo-8-fluoroimidazo[1,2-a]pyridine-3-carbonitrile (CAS 1260657-25-7), molecular formula C8H3BrFN3 and molecular weight 240.03 g/mol, is a CATO reference standard with documented purity and traceability.
6-Bromo-8-fluoroimidazo[1,2-a]pyridine-3-carbonitrile (C8H3BrFN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H3BrFN3 |
| Molecular Weight | 240.03 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
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