Bicalutamide Impurity 9 CAS 393-36-2
| CAS No. | 393-36-2 |
| Molecular Formula | C7H5BrF3N |
| Molecular Weight | 240.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 240.02 g/mol gives Bicalutamide Impurity 9 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Bicalutamide Impurity 9 (CAS 393-36-2), a pharmacopoeial impurity reference standard (molecular formula C7H5BrF3N, MW 240.02 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Bicalutamide Impurity 9 (C7H5BrF3N) is characterized by a nitrile group, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Bicalutamide Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BrF3N |
| Molecular Weight | 240.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bicalutamide Standards
- Bicalutamide Impurity 40 (CAS CATO-C4X-101340)
- Bicalutamide Impurity 13 (CAS 90357-53-2)
- Bicalutamide Impurity 22 (CAS 405-31-2)
- Bicalutamide Impurity 23 (CAS 74926-87-7)
- Bicalutamide EP Impurity M (CAS 151262-57-6)
- Bicalutamide Impurity 10 (CAS 367-67-9)
- Bicalutamide Impurity 14 (Bicalutamide Epoxide Impurity) (CAS 90357-51-0)
- Bicalutamide Impurity 21 (CAS 71515-96-3)
Recommended Standards
- 2-AMINO-4-BROMOBENZOTRIFLUORIDE 5-BROMO-2-(TRIFLUOROMETHYL)ANILINE 5-BROMO-2-TRIFLUOROMETHYL-PHENYLAMINE 5-BROMO-O-(TRIFLUOROMETHYL)ANILINE 5-bromo-2-trifluoromethylaniline 703-91-3 PF10510 (CAS 703-91-3)
- 2-Amino-5-bromobenzotrifluoride (CAS 445-02-3)
- Nilotinib Bromo Impurity (CAS 54962-75-3)
- 6-Bromo-3-cyano-4-fluoro 1H-Indazole (CAS 1000340-94-2)
- Fluticasone Impurity 50 (CAS CATO-C4X-165050)
- Eplerenone Impurity 20 (CAS CATO-C4X-163020)
- Beraprost Impurity 6 (Mixture of Diastereomers) (CAS CATO-C4X-21846)
- Tris(ethylenediamine)rhodium(III) chloride (CAS 14023-02-0)
- 2-Hydroxy-5-(trifluoromethyl)benzaldehyde (CAS 210039-65-9)
- cis-2-Amino-1-cyclopentanecarboxylic Acid Hydrochloride (CAS 18414-30-7)
- N-(4-(N-(3,4-Dimethylisoxazol-5-yl)sulfamoyl)phenyl)-4-methylbenzamide (CAS 301681-54-9)
- 2-((4-Butyl-5-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxy-5-methylphenyl)acetamide (CAS 868256-56-8)
- 4-Bromo-2-hydroxy-6-(trifluoromethyl)benzaldehyde (CAS 2091042-00-9)
- Semaglutide impurity 50 (CAS 2773558-66-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com