1-(6-Chloro-5-nitropyridin-2-yl)ethanone CAS 1260669-91-7
| CAS No. | 1260669-91-7 |
| Molecular Formula | C7H5ClN2O3 |
| Molecular Weight | 200.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(6-Chloro-5-nitropyridin-2-yl)ethanone (CAS 1260669-91-7) is a high-purity analytical reference standard with the molecular formula C7H5ClN2O3 and a molecular weight of 200.58 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 1-(6-Chloro-5-nitropyridin-2-yl)ethanone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 200.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 1-(6-Chloro-5-nitropyridin-2-yl)ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2O3 |
| Molecular Weight | 200.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-(3-Chloro-5-nitropyridin-2-yl)ethanone (CAS 1071691-14-9)
- 1-(5-Chloro-3-nitropyridin-2-yl)ethanone (CAS 1071691-19-4)
- 2-Chloro-6-nitrobenzamide (CAS 107485-64-3)
- 5-Chloro-3-formyl-2-hydroxybenzoic acid (CAS 111870-27-0)
- 2-Chloro-3-nitrobenzamide (CAS 117054-76-9)
- 1-(2-Chloro-5-nitropyridin-4-yl)ethanone (CAS 1214241-91-4)
- 2-Chloro-5-nitro-3-pyridinylethanone (CAS 1256264-86-4)
- 1-(6-Chloro-5-nitropyridin-3-yl)ethan-1-one (CAS 127356-40-5)
Recommended Standards
- 2-Chloroisophthalic acid (CAS 13049-16-6)
- 5-Carbamoyl-3-chloropyridine-2-carboxylic acid (CAS 1200497-79-5)
- 5-Carbamoyl-6-chloropyridine-2-carboxylic acid (CAS 1312772-66-9)
- Benzo[d][1,3]dioxol-5-yl carbonochloridate (CAS 117886-89-2)
- Ethyl 4-(4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 123629-41-4)
- DABMI, 90% (CAS 87963-80-2)
- 5-Amino-1-tert-butyl-3-(3-methylbenzyl)-4-cyanopyrazole (CAS 1185162-28-0)
- (2E)-4-[(3-chlorophenyl)amino]-4-oxobut-2-enoic acid (CAS 36847-88-8)
- Clomiphene Impurity 9 (CAS 14770-94-6)
- Iodoethane-1-d1 (stabilized with copper) (CAS 3652-81-1)
- 3-((4-(Tert-butyl)-N-methylphenyl)sulfonamido)thiophene-2-carboxylic acid (CAS 1111300-43-6)
- Cbz-cis-4-fluoro-Pro-OH (CAS 72204-21-8)
- 3-Fluoro-4-(pyrrolidin-1-ylmethyl)benzaldehyde (CAS 1443353-89-6)
- Des-Ala18-Tirzepatide (CAS CATO-CPTD788955)
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