Tert-butyl 4-(hydroxymethyl)-3-(trifluoromethyl)piperidine-1-carboxylate CAS 1260761-45-2
| CAS No. | 1260761-45-2 |
| Molecular Formula | C12H20F3NO3 |
| Molecular Weight | 283.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Tert-butyl 4-(hydroxymethyl)-3-(trifluoromethyl)piperidine-1-carboxylate (CAS 1260761-45-2), molecular formula C12H20F3NO3 and molecular weight 283.29 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H20F3NO3, Tert-butyl 4-(hydroxymethyl)-3-(trifluoromethyl)piperidine-1-carboxylate contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 283.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Tert-butyl 4-(hydroxymethyl)-3-(trifluoromethyl)piperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H20F3NO3 |
| Molecular Weight | 283.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4-(Boc-amino)-1-(trifluoromethyl)cyclohexanol (CAS 1251923-37-1)
- tert-Butyl 4-(hydroxymethyl)-4-(trifluoromethyl)piperidine-1-carboxylate (CAS 1260893-18-2)
- N-(1H-Benzo[d]imidazol-2-yl)-2-(3-methyl-6-oxopyridazin-1(6H)-yl)acetamide (CAS 1234914-31-8)
- tert-Butyl 3-(2,2,2-Trifluoro-1-hydroxyethyl)piperidine-1-carboxylate (CAS 1283718-04-6)
- (1S)-1-(5-Fluoropyridin-2-yl)ethan-1-ol (CAS 1016227-97-6)
- 3-Nitro-2-phenylthiophene (CAS 18150-94-2)
- 2-(1-methyl-1H-pyrazol-4-yl)pyrimidine-5-carbaldehyde (CAS 1484524-86-8)
- 2-Amino-2-(2-bromophenyl)acetonitrile hydrochloride (CAS 1613253-70-5)
- 5-((3-Mesityl-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methylbenzyl)-2-thioxothiazolidin-4-one (CAS 623934-80-5)
- 2-(6-Chloro-3-methylpyridin-2-yl)propan-2-amine hydrochloride (CAS 1824304-48-4)
- Sinomenine (CAS 115-53-7)
- 2-(1-Methyl-1H-imidazol-2-yl)pyridine (CAS 77429-59-5)
- (2e)-3-{1-[(2-chlorophenyl)methyl]-3,5-dimethyl-1h-pyrazol-4-yl}prop-2-enoic acid (CAS 956740-87-7)
- Semaglutide Impurity 122 (CAS CATO-C4X-2226122)
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