Tert-butyl 4-(aminomethyl)-3-(trifluoromethyl)piperidine-1-carboxylate CAS 1260761-49-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1260761-49-6
Molecular FormulaC12H21F3N2O2
Molecular Weight282.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Tert-butyl 4-(aminomethyl)-3-(trifluoromethyl)piperidine-1-carboxylate CAS 1260761-49-6 chemical structure

Description

The occurrence of Tert-butyl 4-(aminomethyl)-3-(trifluoromethyl)piperidine-1-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Tert-butyl 4-(aminomethyl)-3-(trifluoromethyl)piperidine-1-carboxylate (CAS 1260761-49-6), molecular formula C12H21F3N2O2 and molecular weight 282.30 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Tert-butyl 4-(aminomethyl)-3-(trifluoromethyl)piperidine-1-carboxylate (C12H21F3N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H21F3N2O2
Molecular Weight282.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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