1-(3-Chloro-2-fluorophenyl)cyclopropanecarboxylic Acid CAS 1260763-00-5
| CAS No. | 1260763-00-5 |
| Molecular Formula | C10H8ClFO2 |
| Molecular Weight | 214.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 214.62 g/mol gives 1-(3-Chloro-2-fluorophenyl)cyclopropanecarboxylic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(3-Chloro-2-fluorophenyl)cyclopropanecarboxylic Acid (CAS 1260763-00-5), molecular formula C10H8ClFO2 and molecular weight 214.62 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-Chloro-2-fluorophenyl)cyclopropanecarboxylic Acid (C10H8ClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(3-Chloro-2-fluorophenyl)cyclopropanecarboxylic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClFO2 |
| Molecular Weight | 214.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 1-(2-Chloro-6-fluorophenyl)cyclopropanecarboxylic Acid (CAS 1006876-25-0)
- 7-Chloro-6-fluoro-2-methylchroman-4-one (CAS 111478-29-6)
- 2-(2-Chloro-6-fluorophenyl)cyclopropane-1-carboxylic acid (CAS 1157642-59-5)
- 2-(4-Chloro-3-fluorophenyl)cyclopropane-1-carboxylic acid (CAS 1248362-12-0)
- (3-Chloro-5-fluoro-2-hydroxyphenyl)(cyclopropyl)methanone (CAS 1251197-50-8)
- 1-(4-Chloro-3-fluorophenyl)cyclopropanecarboxylic Acid (CAS 1268444-83-2)
- 2-Chloro-3-ethynyl-4-fluoro-1,5-dimethoxybenzene (CAS 1453211-51-2)
- 7-Chloro-8-fluoro-3,4-dihydrobenzo[b]oxepin-5(2H)-one (CAS 1555192-15-8)
Recommended Standards
- (1R,2R)-2-(4-chloro-2-fluorophenyl)cyclopropane-1-carboxylic acid (CAS 1391625-50-5)
- 2-(3-Chloro-2-fluorophenyl)cyclopropanecarboxylic acid (CAS 1593692-08-0)
- Pamabrom USP Related Compound A (CAS 85-18-7)
- 1-(2-Chloro-4-fluorophenyl)pyrazolidin-3-one (CAS 183586-08-5)
- (2R,3S,4S,5R,6R)-3,4,5-tris(Benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-amine (CAS 150370-50-6)
- 2-amino-2-iminoethyl aminomethanimidothioate dihydrochloride (CAS 36518-79-3)
- 4-(3,3-Difluoroazetidin-1-yl)-3-nitrobenzaldehyde 1779119-84-4 (CAS 1779119-84-4)
- 2-(4-(Dimethylamino)benzylidene)-1h-indene-1,3(2h)-dione (CAS 21889-13-4)
- Methyl 3-(2-(thiophene-2-carbonyl)hydrazine-1-carbothioamido)thiophene-2-carboxylate (CAS 1024316-57-1)
- 4-Ethynyl-5-fluoro-2-methoxypyridine (CAS 1211584-33-6)
- 5-Chloro-2-fluoroisonicotinic acid (CAS 1211532-40-9)
- 2,4-dinitrophenylsulfonyl chloride (CAS 1656-44-6)
- 7-Chloro-2-(3,4-dimethoxyphenyl)-6-ethyl-5-methylpyrazolo[1,5-a]pyrimidine (CAS 1464091-54-0)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
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