ethyl 8-bromo-4-chloro-quinazoline-2-carboxylate CAS 1260859-29-7
| CAS No. | 1260859-29-7 |
| Molecular Formula | C11H18BrClN2O2 |
| Molecular Weight | 325.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
ethyl 8-bromo-4-chloro-quinazoline-2-carboxylate (C11H18BrClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
ethyl 8-bromo-4-chloro-quinazoline-2-carboxylate (CAS 1260859-29-7), molecular formula C11H18BrClN2O2 and molecular weight 325.63 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H18BrClN2O2 |
| Molecular Weight | 325.63 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
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- 2-((4-Fluorophenyl)amino)-4H-[1,3]thiazino[5,6-b]quinoxalin-4-one (CAS 154371-21-8)
- 5-(Difluoromethyl)-6-methoxynicotinonitrile (CAS 1806768-62-6)
- (1-(Pteridin-4-yl)piperidin-3-yl)methanol (CAS 1707581-54-1)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
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