ethyl 7-bromo-4-chloro-1,5-naphthyridine-3-carboxylate CAS 127448-21-9
| CAS No. | 127448-21-9 |
| Molecular Formula | C11H18BrClN2O2 |
| Molecular Weight | 325.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
ethyl 7-bromo-4-chloro-1,5-naphthyridine-3-carboxylate (CAS 127448-21-9), molecular formula C11H18BrClN2O2 and molecular weight 325.63 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, ethyl 7-bromo-4-chloro-1,5-naphthyridine-3-carboxylate is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 325.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures ethyl 7-bromo-4-chloro-1,5-naphthyridine-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H18BrClN2O2 |
| Molecular Weight | 325.63 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- (4-Bromophenyl)(4-chloro-3,5-dimethylphenyl)methanol (CAS 1443341-65-8)
- BTS 44595 (CAS 139520-94-8)
- (2-Bromophenyl)(4-chloro-3,5-dimethylphenyl)methanol (CAS 1443342-88-8)
- Benzalkonium Chloride impurity 11 (CAS 45275-74-9)
- 1,2-DIfluoro-4-methoxymethoxy-benzene (CAS 749230-22-6)
- 2-Acetamido-3-(4-chlorophenyl)acrylic acid (CAS 3617-00-3)
- 4-Bromo-N-(prop-2-yn-1-yl)benzamide (CAS 82225-32-9)
- 4-(Trifluoromethoxy)benzo[d]oxazole-2-carbaldehyde (CAS 1803741-17-4)
- 2-[(2-Piperidin-4-yl-1H-imidazol-1-yl)methyl]pyridine trihydrochloride (CAS 1992996-23-2)
- 5-Methyl-2-oxa-7-azaspiro[3.5]nonane (CAS 1552130-75-2)
- (pyridin-4-ylmethyl)urea (CAS 36226-33-2)
- 2-Methoxybenzene-1,4-diamine (CAS 5307-02-8)
- 5-Methyl-3-phenyl-1-tosyl-1H-1,2,4-triazole (CAS 647376-09-8)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
Why CATO?
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