2-(Chloromethyl)-6-fluoroisonicotinonitrile CAS 1260897-80-0
| CAS No. | 1260897-80-0 |
| Molecular Formula | C7H4ClFN2 |
| Molecular Weight | 170.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Chloromethyl)-6-fluoroisonicotinonitrile.
2-(Chloromethyl)-6-fluoroisonicotinonitrile (CAS 1260897-80-0) is a high-purity analytical reference standard with the molecular formula C7H4ClFN2 and a molecular weight of 170.57 g/mol.
Based on its molecular formula C7H4ClFN2, 2-(Chloromethyl)-6-fluoroisonicotinonitrile contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 170.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4ClFN2 |
| Molecular Weight | 170.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 4-(Chloromethyl)-6-fluoropicolinonitrile (CAS 1393543-76-4)
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Recommended Standards
- 2-Chloro-7-Fluoroimidazo[1,2-a]pyridine (CAS 1260826-05-8)
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- 5-Amino-2-chloro-4-fluorobenzonitrile (CAS 123614-87-9)
- 5-Chloro-6-fluoro-1H-indazole (CAS 1305207-97-9)
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- 2-(Difluoromethyl)-6-methyl-3-nitropyridine-4-acetonitrile (CAS 1805624-53-6)
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