Argatroban Impurity 80 CAS 1260981-49-4

Description

Compared with other compounds in its class, the molecular weight of 143.18 g/mol gives Argatroban Impurity 80 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Argatroban Impurity 80 (CAS 1260981-49-4), a pharmacopoeial impurity reference standard (molecular formula C7H13NO2, MW 143.18 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Argatroban Impurity 80 is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 143.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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