4-(4-Chloro-5-methyl-pyrimidin-2-yl)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester CAS 1261232-48-7
| CAS No. | 1261232-48-7 |
| Molecular Formula | C15H23ClN4O2S |
| Molecular Weight | 358.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Chloro-5-methyl-pyrimidin-2-yl)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester.
4-(4-Chloro-5-methyl-pyrimidin-2-yl)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester (CAS 1261232-48-7) is a high-purity analytical reference standard with the molecular formula C15H23ClN4O2S and a molecular weight of 358.89 g/mol.
4-(4-Chloro-5-methyl-pyrimidin-2-yl)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester (C15H23ClN4O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-Chloro-5-methyl-pyrimidin-2-yl)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H23ClN4O2S |
| Molecular Weight | 358.89 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 6-Chloro-2-(2-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-7(1H)-one (CAS 478258-95-6)
- 6-Chloro-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-5-methylpyrazolo[1,5-a]pyrimidin-7(1H)-one (CAS 383148-61-6)
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Recommended Standards
- tert-Butyl 4-(6-chloro-2-(methylthio)pyrimidin-4-yl)-2-methylpiperazine-1-carboxylate (CAS 1261232-31-8)
- 3-Methoxy-N-methyldesloratadine-d4 (CAS 1189445-21-3)
- tert-Butyl 4-(6-chloro-2-(methylthio)pyrimidin-4-yl)-3-methylpiperazine-1-carboxylate (CAS 1261231-27-9)
- 2-Bromo-5-(difluoromethyl)-3-iodoisonicotinonitrile (CAS 1804660-17-0)
- 1-Isopentyl-5-isopropyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1266931-57-0)
- 2-Methyl-1-(trifluoromethyl)naphthalene (CAS 70109-82-9)
- 1,2-Diaminoethan-1-ol (CAS 83007-95-8)
- 1-Iodo-3-methylimidazo[1,5-a]pyrazin-8-amine (CAS 1823418-87-6)
- Propanedioic acid, 2-butyl-, 1-(1,2-diphenylhydrazide), calcium salt, hydrate (CAS 69365-73-7)
- 4-(4-Methylpiperazin-1-yl)-2-(thiophen-2-yl)quinoline (CAS 156095-20-4)
- 2-(Pyridin-4-yl)-1H-imidazole-4,5-dicarbonitrile (CAS 51294-32-7)
- 2-(4-Hydroxypiperidin-1-yl)-2-phenylacetic acid hydrochloride (CAS 928322-40-1)
- N-(4-bromo-2-methoxyphenyl)-2,2,2-trifluoroacetamide (CAS 870838-52-1)
- Neuroendocrine Regulatory Peptide-1 (rat) (CAS 954420-51-0)
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