2-Chloro-N-(3-(2-phenylmorpholino)propyl)benzamide CAS 954046-88-9
| CAS No. | 954046-88-9 |
| Molecular Formula | C20H23ClN2O2 |
| Molecular Weight | 358.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Chloro-N-(3-(2-phenylmorpholino)propyl)benzamide (CAS 954046-88-9), molecular formula C20H23ClN2O2 and molecular weight 358.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-N-(3-(2-phenylmorpholino)propyl)benzamide (C20H23ClN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H23ClN2O2 |
| Molecular Weight | 358.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-2-((1-(thiophen-2-ylsulfonyl)piperidin-4-yl)oxy)pyridine (CAS 1448044-27-6)
- 5-Chloro-4-(phenylsulfonyl)-N-((tetrahydrofuran-2-yl)methyl)thiazol-2-amine (CAS 852711-89-8)
- 4-Chloro-N'-methyl-N'-[2-(methylsulfanyl)quinazolin-4-yl]benzohydrazide (CAS 341968-18-1)
- 6-Chloro-2-(2-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-7(1H)-one (CAS 478258-95-6)
- 6-Chloro-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-5-methylpyrazolo[1,5-a]pyrimidin-7(1H)-one (CAS 383148-61-6)
- 4-Chloro-N-(4-(4-methylpiperidin-1-yl)-4-oxobutyl)benzenesulfonamide (CAS 881937-57-1)
- 5-Chloro-3-Ethyl-N-[[(2S,4S)-1-Ethyl-4-Fluoropyrrolidin-2-Yl]Methyl]-2-Hydroxy-6-Methoxybenzamide (CAS 140161-12-2)
- 2-{[(5-chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl]sulfanyl}benzoic acid (CAS 318234-17-2)
Recommended Standards
- 1-(4-Chlorophenyl)-2-hydroxy-4-(4-phenyl-1-piperazinyl)-1-butanone (CAS 51037-53-7)
- 3-((4-Chlorophenyl)sulfonyl)-N-(4,5-dimethylthiazol-2-yl)propanamide (CAS 923422-56-4)
- 1-(2,4-Dihydroxy-6-methylphenyl)-2-phenoxyethan-1-one (CAS 956239-87-5)
- n-(6-Amino-1-butyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-chloro-N-isobutylbutanamide (CAS 730949-93-6)
- 5,6-Dihydro-1H-pyridin-2-one (CAS 6052-73-9)
- 6-Nitrobenzoxazole-2(3H)-one (CAS 4694-91-1)
- [2-(3-Methyl-1,2,4-oxadiazol-5-yl)ethyl]amine hydrochloride (CAS 1185295-39-9)
- Ixazomib Impurity 46 (CAS CATO-C4X-126746)
- 2-Bromo-5-(4-methyl-1-piperazinyl)pyrazine (CAS 955050-06-3)
- [1-(3-Fluoro-4-morpholin-4-ylphenyl)ethyl]-methylamine hydrochloride (CAS 1332531-48-2)
- 4-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 937591-48-5)
- 6-(1-Bromoethyl)-N-(4-methylphenyl)-1,3,5-triazine-2,4-diamine (CAS 890094-41-4)
- Docetaxel Impurity 39 (CAS 859498-31-0)
- Biotinyl-CBP501 Affinity Peptide trifluoroacetate salt (CAS 2022956-39-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com