Donepezil-d7 HCl CAS 1261394-20-0
| CAS No. | 1261394-20-0 |
| Molecular Formula | - |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Donepezil-d7 HCl.
CATO supplies Donepezil-d7 HCl (CAS 1261394-20-0), a certified reference material (molecular formula C24H22D7NO3HCl, MW 423.00 g/mol) for analytical method development and quality control.
Structurally, Donepezil-d7 HCl (C24H22D7NO3HCl) contains deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.5, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 423.00 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Donepezil-d7 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H22D7NO3 HCl |
| Molecular Weight | 423.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Donepezil Standards
- Donepezil Impurity 15 (CAS 1023500-88-0)
- Donepezil Impurity 44 (CAS 1026443-48-0)
- Donepezil Impurity 46 (CAS 1034439-43-4)
- Donepezil-d5 (CAS 1128086-25-8)
- Donepezil Impurity 55 (CAS 1189443-74-0 (free base))
- Donepezil Related Compound A HCl (CAS 120011-69-0)
- Donepezil Hydrochloride (CAS 120011-70-3)
- Donepezil Impurity 25 (CAS 120012-04-6)
Recommended Standards
- (2-Aminophenyl)diphenylmethanol (CAS 52744-72-6)
- 2-(2-(2-((2-Ethylhexyl)oxy)ethoxy)ethoxy)ethan-1-ol (CAS 1559-37-1)
- o-Toluic-d7 Acid (CAS 207742-73-2)
- [S-(E)]-2-Ethylidene-1,5-dimethyl-3,3-diphenyl-pyrrolidine (S-EDDP) (CAS 106293-57-6)
- 4-(2-Methoxypyrimidin-5-yl)phenol (CAS 1780278-53-6)
- 2-(5-(4-Ethoxyphenyl)-1H-pyrazol-3-yl)acetonitrile (CAS 1352482-53-1)
- 6-Methoxyimidazo[1,2-b]pyridazine (CAS 17240-33-4)
- 2420-16-8 Benzaldehyde, 3-chloro-4-hydroxy- (8CI)(9CI) 3-Chloro-4-hydroxybenzaldehyde NSC 85482 (CAS 2420-16-8)
- 1-Isopropyl-3-methyl-1H-pyrazole-4-carbonyl chloride (CAS 113100-62-2)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
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