8-(Difluoromethyl)quinoline CAS 1261459-29-3
| CAS No. | 1261459-29-3 |
| Molecular Formula | C10H7F2N |
| Molecular Weight | 179.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-(Difluoromethyl)quinoline.
8-(Difluoromethyl)quinoline (CAS 1261459-29-3), molecular formula C10H7F2N and molecular weight 179.17 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 8-(Difluoromethyl)quinoline (C10H7F2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 179.17 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-(Difluoromethyl)quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F2N |
| Molecular Weight | 179.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)quinoline (CAS 1075184-01-8)
- 4-(Difluoromethyl)quinoline (CAS 1186194-77-3)
- 3-(Difluoromethyl)quinoline (CAS 1186195-11-8)
- 5-(Difluoromethyl)isoquinoline (CAS 1204298-57-6)
- 8-(Difluoromethyl)isoquinoline (CAS 1204298-62-3)
- 7-(Difluoromethyl)isoquinoline (CAS 1204298-71-4)
- 6-(Difluoromethyl)isoquinoline (CAS 1204298-75-8)
- 1-(Difluoromethyl)isoquinoline (CAS 1261577-75-6)
Recommended Standards
- 5-Amino-2,3-dihydrobenzofuran-2-carboxylic acid (CAS 1260877-97-1)
- Methyl (3-formylphenyl)carbamate (CAS 1260852-36-5)
- 7-(Difluoromethyl)quinoline (CAS 1261728-71-5)
- 1-(2,5-Difluorophenyl)cyclopropanecarbonitrile (CAS 1260836-46-1)
- Ethyl 5-(2-((tert-butoxycarbonyl)amino)ethyl)-1H-1,2,4-triazole-3-carboxylate (CAS 311349-57-2)
- (R)-(-)-2-Amino-3-hydroxy-3-methylbutanoic Acid (CAS 2280-48-0)
- 2-(tert-Butyl)-5-cyclopropoxypyridine-4-sulfonamide (CAS 1243283-61-5)
- n-Allyl-3-hydroxy-2-naphthamide (CAS 856055-97-5)
- Metoclopramide Impurity 126 (CAS CATO-C4X-1415126)
- 3-Fluoro-5,6,7,8-tetrahydro-1,7-naphthyridine (CAS 1196153-21-5)
- 3-Fluoro-2-(trifluoromethyl)benzylamine (CAS 771581-62-5)
- 3B-Acetoxybetulinic acid (CAS 10376-50-8)
- 2-methyl-4-(1-methylcyclopropoxy)-1-nitrobenzene (CAS 1626355-70-1)
- Urotensin II-Related Peptide (human, mouse, rat) (CAS 342878-90-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com