1-(Difluoromethyl)isoquinoline CAS 1261577-75-6
| CAS No. | 1261577-75-6 |
| Molecular Formula | C10H7F2N |
| Molecular Weight | 179.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-(Difluoromethyl)isoquinoline (CAS 1261577-75-6), a certified reference material (molecular formula C10H7F2N, MW 179.17 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H7F2N, 1-(Difluoromethyl)isoquinoline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 179.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Difluoromethyl)isoquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7F2N |
| Molecular Weight | 179.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)quinoline (CAS 1075184-01-8)
- 4-(Difluoromethyl)quinoline (CAS 1186194-77-3)
- 3-(Difluoromethyl)quinoline (CAS 1186195-11-8)
- 5-(Difluoromethyl)isoquinoline (CAS 1204298-57-6)
- 8-(Difluoromethyl)isoquinoline (CAS 1204298-62-3)
- 7-(Difluoromethyl)isoquinoline (CAS 1204298-71-4)
- 6-(Difluoromethyl)isoquinoline (CAS 1204298-75-8)
- 8-(Difluoromethyl)quinoline (CAS 1261459-29-3)
Recommended Standards
- 7-(Difluoromethyl)quinoline (CAS 1261728-71-5)
- 5-Amino-2,3-dihydrobenzofuran-2-carboxylic acid (CAS 1260877-97-1)
- Methyl 5-formyl-4-methylpicolinate (CAS 1263060-77-0)
- Methyl (3-formylphenyl)carbamate (CAS 1260852-36-5)
- 2-(1-((Benzyloxy)carbonyl)pyrrolidin-2-yl)-2-methoxyacetic acid (CAS 1353953-71-5)
- Quinuclidin-4-ylmethanamine dihydrochloride (CAS 67496-77-9)
- 3-Bromo-5-fluoro-4-nitrobenzaldehyde (CAS 1805556-89-1)
- tert-Butyl 2-(2-hydroxyethyl)azetidine-1-carboxylate (CAS 1228646-09-0)
- 1-Benzyl-4-ethyl-1H-1,2,4-triazol-5(4H)-one (CAS 535961-34-3)
- 4-Formyl-5-hydroxy-6-methylnicotinic acid (CAS 61547-30-6)
- Ceftibuten Impurity 9 (CAS CATO-C4X-18909)
- 2-Methoxy-2-(1-methyl-1h-pyrazol-4-yl)acetonitrile (CAS 1484437-84-4)
- 5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 310451-82-2)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
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