2-Bromo-3-chlorobenzenesulfonyl chloride CAS 1261646-81-4
| CAS No. | 1261646-81-4 |
| Molecular Formula | C6H3BrCl2O2S |
| Molecular Weight | 289.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Bromo-3-chlorobenzenesulfonyl chloride (C6H3BrCl2O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Bromo-3-chlorobenzenesulfonyl chloride (CAS 1261646-81-4), molecular formula C6H3BrCl2O2S and molecular weight 289.96 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3BrCl2O2S |
| Molecular Weight | 289.96 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 3-Bromo-2-chlorobenzene-1-sulfonyl chloride (CAS 100191-17-1)
- 2-Bromo-5-chlorobenzene-1-sulfonyl chloride (CAS 1037299-72-1)
- 3-Bromo-5-chlorophenylsulfonyl chloride (CAS 1049026-36-9)
- 2-Bromo-6-chlorobenzenesulfonyl chloride (CAS 1261874-16-1)
- 3-bromo-4-chlorobenzene-1-sulfonyl chloride (CAS 195201-10-6)
- 2-bromo-4-chlorobenzene-1-sulfonyl chloride (CAS 929281-63-0)
- 4-Bromo-2-chloro-1-benzenesulfonyl Chloride (CAS 351003-52-6)
- 4-Bromo-3-chlorobenzene-1-sulfonyl chloride (CAS 874801-46-4)
Recommended Standards
- Orforglipron impurity 135 (CAS 2384281-38-1)
- 6,8-Dibromo-2-methylimidazo[1,2-a]pyridine (CAS 860260-49-7)
- 5,7-Dibromo-6-methyl-1H-indazole (CAS 883834-49-9)
- 5-Bromo-2-chlorobenzenesulfonyl Chloride (CAS 81226-68-8)
- N-(Pyrrolidin-3-ylmethyl)pivalamide hydrochloride (CAS 1346602-39-8)
- N-Cyclopentyl-2-(4-(trifluoromethoxy)phenyl)-2H-tetrazole-5-carboxamide (CAS 1396874-71-7)
- 2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-methylpropanenitrile (CAS 338754-05-5)
- Isobutyl(phenyl)sulfane (CAS 13307-61-4)
- 3-[methyl(piperidin-4-yl)amino]propanoic acid dihydrochloride (CAS 1797017-23-2)
- 1-(7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-N-methylmethanamine (CAS 886851-54-3)
- 3-(3,3-Difluoroazetidin-1-yl)-5-fluoropyridine (CAS 1707580-98-0)
- (E)-Dodec-10-en-1-ol (CAS 35237-63-9)
- 3-[4-(Trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 109888-65-5)
- Hexapeptide-1 (CAS CATO-CPTD788821)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com