5-Bromo-2-chlorobenzenesulfonyl Chloride CAS 81226-68-8
| CAS No. | 81226-68-8 |
| Molecular Formula | C6H3BrCl2O2S |
| Molecular Weight | 289.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Bromo-2-chlorobenzenesulfonyl Chloride (CAS 81226-68-8), molecular formula C6H3BrCl2O2S and molecular weight 289.96 g/mol, is a CATO reference standard with documented purity and traceability.
5-Bromo-2-chlorobenzenesulfonyl Chloride (C6H3BrCl2O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-2-chlorobenzenesulfonyl Chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3BrCl2O2S |
| Molecular Weight | 289.96 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 3-Bromo-2-chlorobenzene-1-sulfonyl chloride (CAS 100191-17-1)
- 2-Bromo-5-chlorobenzene-1-sulfonyl chloride (CAS 1037299-72-1)
- 3-Bromo-5-chlorophenylsulfonyl chloride (CAS 1049026-36-9)
- 2-Bromo-3-chlorobenzenesulfonyl chloride (CAS 1261646-81-4)
- 2-Bromo-6-chlorobenzenesulfonyl chloride (CAS 1261874-16-1)
- 3-bromo-4-chlorobenzene-1-sulfonyl chloride (CAS 195201-10-6)
- 2-bromo-4-chlorobenzene-1-sulfonyl chloride (CAS 929281-63-0)
- 4-Bromo-2-chloro-1-benzenesulfonyl Chloride (CAS 351003-52-6)
Recommended Standards
- 4-Bromo-3-chlorobenzene-1-sulfonyl chloride (CAS 874801-46-4)
- 2,3,6,7-Tetrachlorobiphenylene (CAS 7090-41-7)
- 2-Iodo-5-(trifluoromethoxy)pyrazine (CAS 1261633-10-6)
- 5-Iodo-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 126538-82-7)
- Methyl 4-(chlorosulfonyl)-3-methoxybenzoate (CAS 162141-56-2)
- 1-[4-(Methylsulfanyl)phenyl]imidazolidin-2-one (CAS 1040130-00-4)
- 1-(4'-Pentyl-[1,1'-biphenyl]-4-yl)ethan-1-one (CAS 59662-38-3)
- 7-Iodo-2-methylbenzo[d]thiazol-6-amine (CAS 1297528-78-9)
- 4-Hydroxy-3-(2-methylthiazol-4-yl)benzoic acid (CAS 1387557-18-7)
- 3,5-Dichloro-2-(cyclopropylmethoxy)benzaldehyde (CAS 883532-17-0)
- Thieno[3,4-b]thiophene (CAS 250-65-7)
- 2-[(1,5-dimethyl-1H-pyrazol-4-yl)methoxy]aniline (CAS 1006959-24-5)
- Ethyl 2-amino-5-(isopropylcarbamoyl)-4-methylthiophene-3-carboxylate (CAS 886672-89-5)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com