5-Iodo-2-(trifluoromethyl)phenylacetonitrile CAS 1261748-42-8
| CAS No. | 1261748-42-8 |
| Molecular Formula | C9H5F3IN |
| Molecular Weight | 311.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Iodo-2-(trifluoromethyl)phenylacetonitrile (CAS 1261748-42-8) is a high-purity analytical reference standard with the molecular formula C9H5F3IN and a molecular weight of 311.04 g/mol.
The molecular framework of 5-Iodo-2-(trifluoromethyl)phenylacetonitrile (C9H5F3IN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 5-Iodo-2-(trifluoromethyl)phenylacetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5F3IN |
| Molecular Weight | 311.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 2-(2-Iodo-5-(trifluoromethyl)phenyl)acetonitrile (CAS 702641-07-4)
- 1-Ethyl-4-iodo-3-nitro-1h-pyrazole-5-carboxylic acid (CAS 1354703-87-9)
- Methyl 4-iodo-1-methyl-3-nitro-1H-pyrazole-5-carboxylate (CAS 1354703-95-9)
- Methyl 4-iodo-1-methyl-5-nitro-1H-pyrazole-3-carboxylate (CAS 1354704-43-0)
- 3-(4-Iodo-3-nitro-1H-pyrazol-1-yl)propanoic acid (CAS 1354704-48-5)
- Methyl 2-(4-iodo-3-nitro-1H-pyrazol-1-yl)acetate (CAS 1354705-51-3)
- 1-Ethyl-4-iodo-5-nitro-1h-pyrazole-3-carboxylic acid (CAS 1354706-75-4)
- 3-Iodo-2,5,6-trimethoxypyridin-4-ol (CAS 1414864-12-2)
Recommended Standards
- 2-(6-Bromo-3-(difluoromethyl)-5-nitropyridin-2-yl)acetic acid (CAS 1805167-18-3)
- 2-(4-Bromo-5-(difluoromethyl)-3-nitropyridin-2-yl)acetic acid (CAS 1805167-61-6)
- 2-(6-Bromo-5-(difluoromethyl)-3-nitropyridin-2-yl)acetic acid (CAS 1805250-23-0)
- 2-(4-Bromo-6-(difluoromethyl)-5-nitropyridin-3-yl)acetic acid (CAS 1805449-89-1)
- 4-Chloro-6-cyano-7-methoxyquinoline (CAS 398487-31-5)
- 1,2-Dimethyl-8-(trifluoromethyl)quinolin-4(1H)-one (CAS 1208408-56-3)
- (3,4-Difluorophenyl)(5-methylthiophen-2-yl)methanol (CAS 1249578-63-9)
- N-Benzylfuran-2-carboxamide (CAS 10354-48-0)
- 2,4-Diamino-3-Fluoro-4-Oxobutanoic Acid (CAS 72016-54-7)
- (S)-2-((S)-2-Cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoic acid (CAS 402958-96-7)
- N-Nitroso Formoterol Impurity 108 (CAS CATO-C4X-1525108)
- 5-Methyl-1H-pyrazolo[4,3-b]pyridin-3-amine (CAS 52090-86-5)
- 6-Bromo-4-methoxypicolinic acid (CAS 1060805-13-1)
- Peptide 431 (CAS CATO-CPTD788431)
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