2-(3-(Difluoromethyl)-2-hydroxybenzoyl)pyridine CAS 1261807-71-9
| CAS No. | 1261807-71-9 |
| Molecular Formula | C13H9F2NO2 |
| Molecular Weight | 249.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 249.21 g/mol gives 2-(3-(Difluoromethyl)-2-hydroxybenzoyl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(3-(Difluoromethyl)-2-hydroxybenzoyl)pyridine (CAS 1261807-71-9), molecular formula C13H9F2NO2 and molecular weight 249.21 g/mol, is a CATO reference standard with documented purity and traceability.
2-(3-(Difluoromethyl)-2-hydroxybenzoyl)pyridine (C13H9F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(3-(Difluoromethyl)-2-hydroxybenzoyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9F2NO2 |
| Molecular Weight | 249.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(2-(Difluoromethyl)-5-hydroxybenzoyl)pyridine (CAS 1261521-29-2)
- 2-(4-(Difluoromethyl)-2-hydroxybenzoyl)pyridine (CAS 1261660-93-8)
- (3-(Difluoromethyl)-4-hydroxyphenyl)(pyridin-4-yl)methanone (CAS 1261660-98-3)
- 2-(Difluoromethyl)-3-fluoro-6-(methylsulfonyl)benzonitrile (CAS 1672663-82-9)
- 2-(Difluoromethyl)-6-phenylnicotinic acid (CAS 1708208-58-5)
- 4-(Difluoromethyl)-2-phenylpyrimidine-5-carboxamide (CAS 1713713-45-1)
- 2-((Difluoromethyl)sulfonyl)benzo[d]thiazole (CAS 186204-66-0)
- 3-(Difluoromethyl)-5-formyl-6-(trifluoromethyl)picolinonitrile (CAS 1804423-73-1)
Recommended Standards
- Methyl 5-(2,3-difluorophenyl)nicotinate (CAS 1261663-40-4)
- 2-(3-((Trifluoromethyl)sulfonyl)phenyl)acetonitrile (CAS 1301739-15-0)
- (S)-3-Methyl-2-(trifluoromethylsulfonamido)butanoic acid (CAS 130881-11-7)
- 2-Hydrazino-6-(trifluoromethoxy)-1,3-benzothiazole (CAS 133840-98-9)
- 3-Bromo-2-chloro-6-fluoroaniline (CAS 1702023-23-1)
- 1,3-Dimethyl-4-((4-nitro-1h-pyrazol-1-yl)methyl)-1h-pyrazole (CAS 1004644-28-3)
- 3-Hydroxy-3-phenyl-1-(pyridin-2-yl)prop-2-en-1-one (CAS 59276-61-8)
- 2-(4-Bromophenyl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid (CAS 1282577-02-9)
- Posaconazole impurity 249 (CAS CATO-C4X-1208249)
- (S)-3-Aminoheptanoic acid (CAS 161596-37-8)
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