3-(4-Fluorophenyl)-5-trifluoromethylbenzoic acid CAS 1262010-56-9
| CAS No. | 1262010-56-9 |
| Molecular Formula | C14H8F4O2 |
| Molecular Weight | 284.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(4-Fluorophenyl)-5-trifluoromethylbenzoic acid (C14H8F4O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-(4-Fluorophenyl)-5-trifluoromethylbenzoic acid (CAS 1262010-56-9) is a high-purity analytical reference standard with the molecular formula C14H8F4O2 and a molecular weight of 284.21 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(4-Fluorophenyl)-5-trifluoromethylbenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F4O2 |
| Molecular Weight | 284.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Fluorophenyl Standards
- N-(2-Fluorophenyl)-6-(trifluoromethyl)pyridine-3-carboxamide (CAS 1092346-30-9)
- 2-(2-Fluorophenyl)-6-(trifluoromethyl)nicotinamide (CAS 1214337-52-6)
- 2-(4-Fluorophenyl)-6-(trifluoromethyl)nicotinamide (CAS 1214365-98-6)
- 2-(3-Fluorophenyl)-6-(trifluoromethyl)nicotinamide (CAS 1214377-84-0)
- 4-Fluorophenyl 3-(trifluoromethyl)benzoate (CAS 218929-27-2)
- 4-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid (CAS 1135241-36-9)
- 5-(4-Fluorophenyl)-4-nitro-3-phenylisoxazole (CAS 113641-78-4)
- 3-(4-Fluorophenyl)-4-nitro-5-phenylisoxazole (CAS 113641-79-5)
Recommended Standards
- 2'-Fluoro-4-hydroxy-3'-(trifluoromethyl)-[1,1'-biphenyl]-3-carbaldehyde (CAS 1261925-70-5)
- 2-(2-{[(2,2,2-trifluoroethoxy)carbonyl]amino}-1,3-thiazol-4-yl)acetic acid (CAS 1306644-88-1)
- 2'-Fluoro-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 1261896-07-4)
- Methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate (CAS 144740-59-0)
- 2-(2,2-Difluoro-1-methylcyclopropyl)ethan-1-amine hydrochloride (CAS 1955541-55-5)
- (5-Amino-1-ethyl-1H-pyrazol-3-yl)(2-methylpiperidin-1-yl)methanone (CAS 1856069-78-7)
- 5-((2-Nitrophenoxy)methyl)furan-2-carboxylic acid (CAS 364621-84-1)
- 2-(2-(2-(4-Fluorophenyl)thiazol-4-yl)ethyl)isoindoline-1,3-dione (CAS 860786-86-3)
- Tert-butyl (2-bromo-4-methylthiazol-5-yl)carbamate (CAS 1255095-03-4)
- (E)-5-(2-(7-Chloro-1H-indol-4-yl)vinyl)-N-(2-methyl-6-(piperazin-1-yl)pyrimidin-4-yl)thiazol-2-amine (CAS 936845-71-5)
- 1-[4-(aminomethyl)phenyl]piperidin-2-one (CAS 444002-98-6)
- 4-Methyl-1-(2-(trifluoromethyl)benzyl)-1H-pyrazol-5-amine (CAS 1152526-49-2)
- Calcium 7,7-dimethyloctanoate (CAS 27253-33-4)
- Des-Ala21-Tirzepatide (CAS CATO-CPTD788952)
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