Orbifloxacin EP Impurity D CAS 126458-22-8
| CAS No. | 126458-22-8 |
| Molecular Formula | C19H21F2N3O4 |
| Molecular Weight | 393.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Orbifloxacin EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Orbifloxacin EP Impurity D (CAS 126458-22-8), a pharmacopoeial impurity reference standard (molecular formula C19H21F2N3O4, MW 393.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Orbifloxacin EP Impurity D (C19H21F2N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H21F2N3O4 |
| Molecular Weight | 393.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Orbifloxacin Standards
- Orbifloxacin EP Impurity E (CAS CATO-C4X-25679)
- Orbifloxacin (CAS 113617-63-3)
- Orbifloxacin-d4 (CAS CATO-CCAD303465)
- Orbifloxacin EP Impurity C (CAS 126457-99-6)
- Orbifloxacin impurity 14 (CAS CATO-C4X-256714)
- Orbifloxacin EP Impurity G (CAS CATO-C4X-25676)
- Orbifloxacin impurity 11 (CAS CATO-C4X-256711)
- Orbifloxacin Impurity 3 (CAS CATO-C4X-25673)
Recommended Standards
- 3-(6-(N,N-diethylsulfamoyl)-2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanoic acid (CAS 1171865-50-1)
- MMV-390048 (CAS 1314883-11-8)
- Osimertinib Impurity 90 (CAS CATO-C4X-204590)
- Ethyl 2-(4-trifluoromethoxyphenyl)-4-phenylthiazole-5-carboxylate (CAS 1965304-81-7)
- Nebivolol EP Impurity A (CAS 1416402-13-5)
- Indobufen Impurity 17 (CAS 104-03-0)
- Pitavastatin Impurity 36 (CAS CATO-C4X-103736)
- 7-(Ethylthio)-3-(phenylsulfonyl)-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-amine (CAS 1547758-17-7)
- 2-((tert-Butoxycarbonyl)amino)-3,5-dimethylbenzoicacid (CAS 669713-57-9)
- Indapamide Impurity 14 (CAS 604787-44-2)
- 2-(4-Chlorophenoxy)-2-methyl-1-methylethyl Ester Propanoic Acid (CAS 64416-88-2)
- tert-butyl 4-((4-chloro-5-methylpyrimidin-2-yl)(methyl)amino)piperidine-1-carboxylate (CAS 1261234-12-1)
- 2-Ethylfuran (CAS 3208-16-0)
- Semaglutide Impurity 190 (CAS CATO-C4X-2226190)
Why CATO?
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