Orbifloxacin EP Impurity E CAS CATO-C4X-25679
| CAS No. | CATO-C4X-25679 |
| Molecular Formula | C19H20F3N3O3 |
| Molecular Weight | 395.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Orbifloxacin EP Impurity E (CAS CATO-C4X-25679, C19H20F3N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Orbifloxacin EP Impurity E is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 395.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Orbifloxacin EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H20F3N3O3 |
| Molecular Weight | 395.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Orbifloxacin Standards
- Orbifloxacin (CAS 113617-63-3)
- Orbifloxacin EP Impurity D (CAS 126458-22-8)
- Orbifloxacin-d4 (CAS CATO-CCAD303465)
- Orbifloxacin EP Impurity C (CAS 126457-99-6)
- Orbifloxacin impurity 14 (CAS CATO-C4X-256714)
- Orbifloxacin EP Impurity G (CAS CATO-C4X-25676)
- Orbifloxacin impurity 11 (CAS CATO-C4X-256711)
- Orbifloxacin Impurity 3 (CAS CATO-C4X-25673)
Recommended Standards
- N-[(1E)-{[(2-fluorophenyl)methoxy]imino}methyl]-4-methoxy-2-phenoxypyridine-3-carboxamide (CAS 478262-42-9)
- N-[(1E)-[(Benzyloxy)imino]methyl]-2-(4-fluorophenoxy)-4-methoxypyridine-3-carboxamide (CAS 341966-66-3)
- N-((3-Phenyl-1,2,4-oxadiazol-5-yl)methyl)-2-(thiophene-3-carboxamido)oxazole-4-carboxamide (CAS 1351596-34-3)
- n-((4-(Carboxymethoxy)phenyl)sulfonyl)-n-(2-methoxyphenyl)glycine (CAS 551930-31-5)
- Methotrexate Impurity N5 (CAS 56364-06-8)
- Pantoprazole Impurity 59 (CAS 562074-62-8)
- Risperidone Impurity 32 (CAS 108855-18-1)
- N,3-Dimethyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazole-5-carboxamide (CAS 160205-16-3)
- 2-(3-(((1-Hydroxybutan-2-yl)amino)methyl)-1H-indol-1-yl)acetic acid (CAS 1279201-43-2)
- 1H-Isoindole, 2,3-dihydro-4-methyl-, hydrochloride (1:1) (CAS 1956331-04-6)
- Methyl 4-Hydroxy-2,5-dimethylbenzoate (CAS 27023-05-8)
- 3-(4-Bromophenyl)-1-(2-methoxyphenyl)propan-1-one (CAS 898761-01-8)
- 4-Chloro-N-cyclopropylaniline (CAS 257946-76-2)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com