(4-(2-Chloro-4-nitrophenyl)piperazin-1-yl)(3-(4-hydroxyphenyl)-5-methylisoxazol-4-yl)methanone CAS 1264870-21-4
| CAS No. | 1264870-21-4 |
| Molecular Formula | C21H19ClN4O5 |
| Molecular Weight | 442.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(4-(2-Chloro-4-nitrophenyl)piperazin-1-yl)(3-(4-hydroxyphenyl)-5-methylisoxazol-4-yl)methanone (CAS 1264870-21-4), molecular formula C21H19ClN4O5 and molecular weight 442.85 g/mol, is a CATO reference standard with documented purity and traceability.
(4-(2-Chloro-4-nitrophenyl)piperazin-1-yl)(3-(4-hydroxyphenyl)-5-methylisoxazol-4-yl)methanone (C21H19ClN4O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), (4-(2-Chloro-4-nitrophenyl)piperazin-1-yl)(3-(4-hydroxyphenyl)-5-methylisoxazol-4-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H19ClN4O5 |
| Molecular Weight | 442.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618427-30-8)
- (E)-{[3-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)phenyl]methylidene}(methyl)oxidoazanium (CAS 321432-40-0)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(4-methoxyphenyl)-1-methyl-1H-imidazole-5-carboxamide (CAS 339278-15-8)
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- 2-{N-[2-chloro-5-(trifluoromethyl)phenyl]methanesulfonamido}-N-(2,4-difluorophenyl)acetamide (CAS 478067-38-8)
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- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-5-methyl-2-(4-nitrobenzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860786-15-8)
Recommended Standards
- N-benzyl-4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonamide (CAS 344278-17-7)
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- 3-[3-(Benzyloxy)thiophen-2-yl]-1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}urea (CAS 303147-90-2)
- 2-((4-Allyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-chloro-3-(trifluoromethyl)phenyl)acetamide (CAS 577770-76-4)
- 2-(Benzylthio)ethan-1-amine (CAS 1007-54-1)
- 7-Chloro-2-iodofuro[3,2-b]pyridine (CAS 1071540-54-9)
- 5-Methoxy-2-(methylsulfonyl)benzonitrile (CAS 2044705-00-0)
- 4-[3-(pyrrolidin-1-yl)propoxy]aniline (CAS 343965-79-7)
- 21-Deoxyprednisolone 17alpha-Propionate (CAS 20424-00-4)
- 1-(P-tolyl)ethan-1-one oxime (CAS 2089-33-0)
- 6H-Imidazo[4,5-d]thiazole (CAS 25336-15-6)
- Ethyl 2-(2-phenylthiazolo[3,2-b][1,2,4]triazol-6-yl)acetate (CAS 66870-63-1)
- 4-Amino-1-[(2R,3S,4R,5R)-3,4-difluoro-5-(hydroxymethyl)oxolan-2-Yl]pyrimidin-2-one (CAS 128496-20-8)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
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