1-(3,5-Dichloropyridin-2-yl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid CAS 1265323-91-8
| CAS No. | 1265323-91-8 |
| Molecular Formula | C10H4Cl2F3N3O2 |
| Molecular Weight | 326.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3,5-Dichloropyridin-2-yl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid.
CATO supplies 1-(3,5-Dichloropyridin-2-yl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (CAS 1265323-91-8), a certified reference material (molecular formula C10H4Cl2F3N3O2, MW 326.06 g/mol) for analytical method development and quality control.
1-(3,5-Dichloropyridin-2-yl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (C10H4Cl2F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3,5-Dichloropyridin-2-yl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H4Cl2F3N3O2 |
| Molecular Weight | 326.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloropyridin Standards
- 5-{[(2,6-dichloropyridin-4-yl)amino]methylidene}-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 863785-65-3)
- N-(3,5-Dichloropyridin-4-yl)-7-methoxybenzofuran-4-carboxamide (CAS 185400-39-9)
- Ethyl 2-(((2,6-dichloropyridin-4-yl)methyl)sulfonyl)acetate (CAS 286436-13-3)
- Methyl 2-(((2,6-dichloropyridin-3-yl)methyl)amino)benzoate (CAS 58596-73-9)
- 2-(2,6-Dichloropyridin-4-yl)-5-fluoro-4H-benzo[d][1,3]oxazin-4-one (CAS 219139-72-7)
- N'-((2,6-dichloropyridin-3-yl)methylene)-4-methylbenzenesulfonohydrazide (CAS 1820748-57-9)
- N'-((2,4-Dichloropyridin-3-yl)methylene)-4-methylbenzenesulfonohydrazide (CAS 2586233-02-3)
- N-(2-(3,5-Dichloropyridin-2-yl)phenyl)-2-methylfuran-3-carboxamide (CAS 824952-75-2)
Recommended Standards
- 1-(2,6-Dichloro-4-(trifluoromethyl)phenyl)-4-nitro-1H-pyrazole (CAS 106204-45-9)
- 3-Iodo-2-methyl-7-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 1421786-77-7)
- 3,4-Bis(bromomethyl)-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy Radical (CAS 229621-20-9)
- 3-Iodo-1-methyl-5-(trifluoromethyl)-1H-indazole (CAS 1426425-20-8)
- 3-Chloro-5-isopropoxybenzoic Acid (CAS 1369810-45-6)
- 5-(2,3-Dimethylphenoxy)furan-2-carbaldehyde (CAS 1082167-93-8)
- 5-Cyano-4-cyclopropoxypicolinamide (CAS 1243451-01-5)
- Lercanidipine Impurity 33 (CAS 927-73-1)
- 4-Amino-5-fluoro-8-methylquinoline-3-carboxylic acid (CAS 1315349-91-7)
- DL-Glyceraldehyde-2- (CAS 71122-43-5)
- 2-Methoxy-4-(2'-nitrovinyl)phenyl-2-acetamido-2-deoxy-beta-glucopyranoside (CAS 70622-74-1)
- N-(2,4-difluorophenyl)-2,8-dimethylimidazo[1,2-a]pyridine-3-carboxamide (CAS 477852-37-2)
- 3-(5,6-Dichlorobenzo[d]thiazol-2-yl)pyridin-2(1H)-one (CAS 400075-89-0)
- Cyclopeptide-5 (CAS 197172-76-2)
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