5-{[(2,6-dichloropyridin-4-yl)amino]methylidene}-2,2-dimethyl-1,3-dioxane-4,6-dione CAS 863785-65-3
| CAS No. | 863785-65-3 |
| Molecular Formula | C12H10Cl2N2O4 |
| Molecular Weight | 317.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-{[(2,6-dichloropyridin-4-yl)amino]methylidene}-2,2-dimethyl-1,3-dioxane-4,6-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-{[(2,6-dichloropyridin-4-yl)amino]methylidene}-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 863785-65-3) is a high-purity analytical reference standard with the molecular formula C12H10Cl2N2O4 and a molecular weight of 317.12 g/mol.
5-{[(2,6-dichloropyridin-4-yl)amino]methylidene}-2,2-dimethyl-1,3-dioxane-4,6-dione (C12H10Cl2N2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-{[(2,6-dichloropyridin-4-yl)amino]methylidene}-2,2-dimethyl-1,3-dioxane-4,6-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10Cl2N2O4 |
| Molecular Weight | 317.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related dichloropyridin Standards
- Ethyl 2-(((2,6-dichloropyridin-4-yl)methyl)sulfonyl)acetate (CAS 286436-13-3)
- Methyl 2-(((2,6-dichloropyridin-3-yl)methyl)amino)benzoate (CAS 58596-73-9)
- 2-(2,6-Dichloropyridin-4-yl)-5-fluoro-4H-benzo[d][1,3]oxazin-4-one (CAS 219139-72-7)
- 1-(3,5-Dichloropyridin-2-yl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (CAS 1265323-91-8)
- Ethyl 2-(2,6-dichloropyridin-3-yl)-5-methyl-2H-1,2,3-triazole-4-carboxylate (CAS 1431727-79-5)
- Ethyl 2-(3,5-dichloropyridin-2-yl)-5-methyl-2H-1,2,3-triazole-4-carboxylate (CAS 1431728-58-3)
- 8-(3,5-Dichloropyridin-4-yl)-2,8-diazaspiro[4.5]Decan-1-one (CAS 1221567-78-7)
- Ethyl 2-[(3,5-dichloropyridin-2-yl)sulfonyl]acetate (CAS 478049-31-9)
Recommended Standards
- 4-[(4-Iodophenyl)carbonyl]morpholine (CAS 79271-22-0)
- 6-Bromo-4-(6-fluoropyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile (CAS 2222756-24-1)
- 4-[(3-Iodophenyl)carbonyl]morpholine (CAS 349118-63-4)
- n-(4-Iodophenyl)tetrahydrofuran-2-carboxamide (CAS 438455-85-7)
- (2R,3R)-2,3-dihydroxy-4-oxo-4-(p-tolylamino)butanoic acid (CAS 206761-79-7)
- 6-Methyl-2-(p-tolyl)-4,5-dihydropyridazin-3(2H)-one (CAS 76270-11-6)
- Methyl 3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxylate 1-oxide (CAS 1221792-60-4)
- [1-(3,4-dichlorobenzoyl)-4-fluoro-4-piperidinyl]methyl 4-fluorobenzenesulfonate (CAS 477857-55-9)
- 1-(Tetrahydro-1,1-dioxido-3-thienyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1233526-31-2)
- N-(2-(Methacryloyloxy)ethyl)-N,N-dimethyltetradecan-1-aminium bromide (CAS 93963-45-2)
- 1-(4-Isopropylphenyl)pent-4-en-1-ol (CAS 185901-83-1)
- Ethyl 2-ethyl-3-hydroxybutanoate (CAS 5465-11-2)
- 2-(3,5-Dichlorophenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1369070-69-8)
- Palmitoyl Tripeptide -5 · 2 TFA (CAS 623172-56-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com