6-(Difluoromethyl)pyrimidin-4(3H)-one CAS 126538-89-4
| CAS No. | 126538-89-4 |
| Molecular Formula | C5H4F2N2O |
| Molecular Weight | 146.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 146.09 g/mol gives 6-(Difluoromethyl)pyrimidin-4(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-(Difluoromethyl)pyrimidin-4(3H)-one (CAS 126538-89-4), molecular formula C5H4F2N2O and molecular weight 146.09 g/mol, is a CATO reference standard with documented purity and traceability.
6-(Difluoromethyl)pyrimidin-4(3H)-one (C5H4F2N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-(Difluoromethyl)pyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4F2N2O |
| Molecular Weight | 146.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)pyrimidin-5-ol (CAS 100991-19-3)
- 1-(Difluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 1216244-84-6)
- 1-(Difluoromethyl)-1h-imidazole-2-carbaldehyde (CAS 1248811-92-8)
- 6-(Difluoromethyl)pyrazin-2(1H)-one (CAS 1261630-68-5)
- 1-(Difluoromethyl)-1H-pyrazole-3-carbaldehyde (CAS 1432681-54-3)
- 4-(Difluoromethyl)pyrimidin-2(1H)-one (CAS 1522243-39-5)
- 5-(Difluoromethyl)furan-2-carbaldehyde (CAS 152932-57-5)
- 5-(Difluoromethyl)-3-Furaldehyde (CAS 153026-75-6)
Recommended Standards
- 4,5-Difluorobenzene-1,2-diol (CAS 147300-08-1)
- 2,3-Difluoro-1,4-benzenediol (CAS 124728-90-1)
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- 2,5-Difluoro-4-methoxypyrimidine (CAS 123038-80-2)
- (3E,5E)-1-Benzyl-3,5-bis(phenylmethylidene)piperidin-4-one (CAS 910784-44-0)
- 3-(5-(Tert-butoxycarbonyl)-5H-pyrido[4,3-b]indol-7-yl)propanoic acid (CAS 2267291-24-5)
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