Deferasirox Impurity 9 CAS 1266741-05-2
| CAS No. | 1266741-05-2 |
| Molecular Formula | C22H17N3O4 |
| Molecular Weight | 387.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Deferasirox Impurity 9 (CAS 1266741-05-2, C22H17N3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Deferasirox Impurity 9 (C22H17N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Deferasirox Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H17N3O4 |
| Molecular Weight | 387.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
Related Deferasirox Standards
- Deferasirox Impurity 14 (CAS 524746-13-2)
- Deferasirox Impurity N2 (CAS 524746-12-1)
- Deferasirox-d4 (CAS 1133425-75-8)
- Deferasirox EP Impurity E (CAS 201530-79-2)
- Deferasirox (CAS 201530-41-8)
- Deferasirox EP Impurity C (CAS 201530-78-1)
- Deferasirox EP Impurity D (CAS 2254105-61-6)
- Deferasirox Impurity 2 (CAS CATO-C4X-14382)
Recommended Standards
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